Cellosaurus cell line COLO 720E (CVCL

Cellosaurus COLO 720E (CVCL_1995)

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Cell line name

COLO 720E

Synonyms

COLO 720 E; COLO-720E; COLO720E; Colo720E; Colorado 720E

Accession

CVCL_1995

Resource Identification Initiative

To cite this cell line use: COLO 720E (RRID:CVCL_1995)

Comments

Problematic cell line: Partially contaminated. Some stocks are contaminated by COLO 704 (Cellosaurus=CVCL_AV69).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00438.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala138Val (c.413C>T); ClinVar=VCV000184863; Zygosity=Heterozygous (PubMed=24023729).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys373Argfs*49 (c.1118delA); ClinVar=VCV001052297; Zygosity=Heterozygous (PubMed=24023729).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_1863 ! COLO 720L

Sex of cell

Female

Age at sampling

73Y

Category

Cancer cell line

STR profile

Source(s): PubMed=22710073

Markers:

Amelogenin	X
CSF1PO	11,13
D2S1338	18,24
D3S1358	15,17
D5S818	10,11
D7S820	10
D8S1179	10,13
D13S317	8,11
D16S539	11
D18S51	12,16
D19S433	13,15.2
D21S11	28,32.2
FGA	21,25
TH01	9
TPOX	11
vWA	14

Web pages

Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

Publications

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=24023729; DOI=10.1371/journal.pone.0072162; PMCID=PMC3762837
Michael S. Anglesio, Kimberly C. Wiegand, Nataliya Melnyk, Christine Chow, Clara M. Salamanca, Leah M. Prentice, Janine Senz, Winnie Yang, Monique A. Spillman, Dawn R. Cochrane, Karey Shumansky ...Show all 14 authors... , Sohrab P. Shah, Steve E. Kalloger, David G. Huntsman; Show fewer authors
Type-specific cell line models for type-specific ovarian cancer research.
PLoS ONE 8:e72162.1-e72162.13(2013)

Cross-references

Cell line databases/resources

CLO; CLO_0002556
CLDB; cl845
cancercelllines; CVCL_1995

Encyclopedic resources

Wikidata; Q54814141

Gene expression databases

GEO; GSM711727

Polymorphism and mutation databases

Cosmic; 688126
Cosmic; 1707568
IARC_TP53; 21240

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number