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Cellosaurus COLO 206F (CVCL_1988)

[Text version]
Cell line name COLO 206F
Synonyms Colo-206F; COLO-206F; Colo 206F; COLO206F; COLO 206; COLO206; Colorado 206F
Accession CVCL_1988
Resource Identification Initiative To cite this cell line use: COLO 206F (RRID:CVCL_1988)
Comments Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~2-3 days (DSMZ=ACC-21).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*01:01,02:01
HLA-BB*07:02,08:01
HLA-CC*07:01,07:01
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4V92 (COLO206F-AR)
Originate from same individual CVCL_9976 ! COLO 197
CVCL_9977 ! COLO 200
CVCL_1987 ! COLO 201
CVCL_0218 ! COLO 205
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-21

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,18
D3S135816
D5S81810,13
D7S8209,10
D8S11799,14
D13S31710,12
D16S53912,13
D18S5118
D19S43313,14
D21S1130.2,33.2
FGA21,23
Penta D9,11
Penta E13,15
TH018,9
TPOX11
vWA15

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=6277475
Richard J. Frampton, Larry J. Suva, John Allan Eisman, David M. Findlay, George Eugene Moore, Jane M. Moseley, Thomas John Martin;
Presence of 1,25-dihydroxyvitamin D3 receptors in established human cancer cell lines in culture.
Cancer Res. 42:1116-1119(1982)

PubMed=8464898; DOI=10.1073/pnas.90.7.2842; PMCID=PMC46192
Michael J. Browning, Peter Krausa, Andrew J. Rowan, David C. Bicknell, Julia Gwynaeth Bodmer, Walter Fred Bodmer;
Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.
Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993)

PubMed=10051639; DOI=10.1073/pnas.96.5.2316; PMCID=PMC26781
Jason Alexander Efstathiou, Dan Liu, James M.D. Wheeler, Hee C. Kim, Nicholas E. Beck, Mohammad Ilyas, Anastasios J. Karayiannakis, Neil James Mortensen, Witold Andrzej Wladyslaw Kmiot, Raymond John Playford, Massimo Pignatelli, Walter Fred Bodmer;
Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells.
Proc. Natl. Acad. Sci. U.S.A. 96:2316-2321(1999)

PubMed=11668190; DOI=10.1177/002215540104901105
Hilmar Quentmeier, Mary Osborn, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler;
Immunocytochemical analysis of cell lines derived from solid tumors.
J. Histochem. Cytochem. 49:1369-1378(2001)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Karin Bracht, Angela M. Nicholls, Ying Liu, Walter Fred Bodmer;
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849
Andreas Schlicker, Garry Beran, Christine M. Chresta, Gael McWalter, Alison Pritchard, Susie Weston, Sarah Runswick, Sara Davenport, Kerry Heathcote, Denis Alferez Castro, George Orphanides ...Show all 13 authors... , Tim French, Lodewyk F.A. Wessels; Show fewer authors
Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-21
ECACC; 93052620
Cell line databases/resources CLO; CLO_0002570
CLDB; cl864
cancercelllines; CVCL_1988
Cell_Model_Passport; SIDM00822
ColonAtlas; COLO206F
DSMZCellDive; ACC-21
LINCS_LDP; LCL-1159
Anatomy/cell type resources BTO; BTO_0002199
Chemistry resources PharmacoDB; COLO206F_215_2019
Encyclopedic resources Wikidata; Q54814077
Experimental variables resources EFO; EFO_0006554
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM206460
GEO; GSM274776
GEO; GSM513935
GEO; GSM514188
GEO; GSM784009
GEO; GSM1374453
Polymorphism and mutation databases Cosmic; 2760082
Progenetix; CVCL_1988
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001002554
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number36