ID   COLO 206F
AC   CVCL_1988
SY   Colo-206F; COLO-206F; Colo 206F; COLO206F; COLO 206; COLO206; Colorado 206F
DR   BTO; BTO_0002199
DR   CLO; CLO_0002570
DR   EFO; EFO_0006554
DR   CLDB; cl864
DR   ArrayExpress; E-MTAB-2706
DR   cancercelllines; CVCL_1988
DR   Cell_Model_Passport; SIDM00822
DR   ColonAtlas; COLO206F
DR   Cosmic; 2760082
DR   DSMZ; ACC-21
DR   DSMZCellDive; ACC-21
DR   ECACC; 93052620
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001002554
DR   GEO; GSM206460
DR   GEO; GSM274776
DR   GEO; GSM513935
DR   GEO; GSM514188
DR   GEO; GSM784009
DR   GEO; GSM1374453
DR   LINCS_LDP; LCL-1159
DR   PharmacoDB; COLO206F_215_2019
DR   Progenetix; CVCL_1988
DR   Wikidata; Q54814077
RX   PubMed=6277475;
RX   PubMed=8464898;
RX   PubMed=10051639;
RX   PubMed=11668190;
RX   PubMed=20606684;
RX   PubMed=23272949;
RX   PubMed=25485619;
RX   PubMed=26589293;
RX   PubMed=28196595;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: AstraZeneca Colorectal cell line (AZCL) panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: ~2-3 days (DSMZ=ACC-21).
CC   HLA typing: A*01:01,02:01; B*07:02,08:01; C*07:01,07:01 (PubMed=26589293).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): DSMZ=ACC-21
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 10,12
ST   D16S539: 12,13
ST   D18S51: 18
ST   D19S433: 13,14
ST   D21S11: 30.2,33.2
ST   D2S1338: 17,18
ST   D3S1358: 16
ST   D5S818: 10,13
ST   D7S820: 9,10
ST   D8S1179: 9,14
ST   FGA: 21,23
ST   Penta D: 9,11
ST   Penta E: 13,15
ST   TH01: 8,9
ST   TPOX: 11
ST   vWA: 15
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9976 ! COLO 197
OI   CVCL_9977 ! COLO 200
OI   CVCL_1987 ! COLO 201
OI   CVCL_0218 ! COLO 205
SX   Male
AG   70Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 36
CH   CVCL_4V92 ! COLO206F-AR
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn, Christiaan
RA   Durinck, Steffen
RA   Stawiski, Eric W.
RA   Haverty, Peter M.
RA   Jiang, Zhao-Shi
RA   Liu, Han-Bin
RA   Degenhardt, Jeremiah
RA   Mayba, Oleg
RA   Gnad, Florian
RA   Liu, Jin-Feng
RA   Pau, Gregoire
RA   Reeder, Jens
RA   Cao, Yi
RA   Mukhyala, Kiran
RA   Selvaraj, Suresh K.
RA   Yu, Ma-Mie
RA   Zynda, Gregory J.
RA   Brauer, Matthew J.
RA   Wu, Thomas D.
RA   Gentleman, Robert Clifford
RA   Manning, Gerard
RA   Yauch, Robert L.
RA   Bourgon, Richard
RA   Stokoe, David
RA   Modrusan, Zora
RA   Neve, Richard M.
RA   de Sauvage, Frederic J.
RA   Settleman, Jeffrey
RA   Seshagiri, Somasekar
RA   Zhang, Ze-Min
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028;
RA   Bracht, Karin
RA   Nicholls, Angela M.
RA   Liu, Ying
RA   Bodmer, Walter Fred
RT   "5-fluorouracil response in a large panel of colorectal cancer cell
RT   lines is associated with mismatch repair deficiency.";
RL   Br. J. Cancer 103:340-346(2010).
//
RX   PubMed=11668190; DOI=10.1177/002215540104901105;
RA   Quentmeier, Hilmar
RA   Osborn, Mary
RA   Reinhardt, Julia
RA   Zaborski, Margarete
RA   Drexler, Hans Gunther
RT   "Immunocytochemical analysis of cell lines derived from solid
RT   tumors.";
RL   J. Histochem. Cytochem. 49:1369-1378(2001).
//
RX   PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849;
RA   Schlicker, Andreas
RA   Beran, Garry
RA   Chresta, Christine M.
RA   McWalter, Gael
RA   Pritchard, Alison
RA   Weston, Susie
RA   Runswick, Sarah
RA   Davenport, Sara
RA   Heathcote, Kerry
RA   Castro, Denis Alferez
RA   Orphanides, George
RA   French, Tim
RA   Wessels, Lodewyk F.A.
RT   "Subtypes of primary colorectal tumors correlate with response to
RT   targeted treatment in colorectal cell lines.";
RL   BMC Med. Genomics 5:66.1-66.15(2012).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, Agda Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=8464898; DOI=10.1073/pnas.90.7.2842; PMCID=PMC46192;
RA   Browning, Michael J.
RA   Krausa, Peter
RA   Rowan, Andrew J.
RA   Bicknell, David C.
RA   Bodmer, Julia Gwynaeth
RA   Bodmer, Walter Fred
RT   "Tissue typing the HLA-A locus from genomic DNA by sequence-specific
RT   PCR: comparison of HLA genotype and surface expression on colorectal
RT   tumor cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:2842-2845(1993).
//
RX   PubMed=6277475;
RA   Frampton, Richard J.
RA   Suva, Larry J.
RA   Eisman, John Allan
RA   Findlay, David M.
RA   Moore, George Eugene
RA   Moseley, Jane M.
RA   Martin, Thomas John
RT   "Presence of 1,25-dihydroxyvitamin D3 receptors in established human
RT   cancer cell lines in culture.";
RL   Cancer Res. 42:1116-1119(1982).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers, Jelle
RA   Boegel, Sebastian
RA   Bukur, Thomas
RA   Byl, Marius
RA   Goerges, Sebastian
RA   Sorn, Patrick
RA   Loewer, Martin
RA   Sahin, Ugur
RA   Castle, John C.
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=10051639; DOI=10.1073/pnas.96.5.2316; PMCID=PMC26781;
RA   Efstathiou, Jason Alexander
RA   Liu, Dan
RA   Wheeler, James M.D.
RA   Kim, Hee C.
RA   Beck, Nicholas E.
RA   Ilyas, Mohammad
RA   Karayiannakis, Anastasios J.
RA   Mortensen, Neil James
RA   Kmiot, Witold Andrzej Wladyslaw
RA   Playford, Raymond John
RA   Pignatelli, Massimo
RA   Bodmer, Walter Fred
RT   "Mutated epithelial cadherin is associated with increased
RT   tumorigenicity and loss of adhesion and of responsiveness to the
RT   motogenic trefoil factor 2 in colon carcinoma cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 96:2316-2321(1999).
//