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Cellosaurus CL-50IIa (CVCL_1985)

[Text version]
Cell line name CL-50IIa
Synonyms CL 50-IIa; CL50IIa
Accession CVCL_1985
Resource Identification Initiative To cite this cell line use: CL-50IIa (RRID:CVCL_1985)
Comments Doubling time: ~50-60 hours (DSMZ=ACC-623).
Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Rat hepatocellular carcinoma (NCIt: C60416)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar-AF/Han.
Hierarchy Parent: CVCL_WU98 (CL-50)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=2895109; DOI=10.1007/BF00417823
Kerler R., Rabes H.M.
Preneoplastic rat liver cells in vitro: slow progression without promoters, hormones, or growth factors.
J. Cancer Res. Clin. Oncol. 114:113-123(1988)

PubMed=2684400
Suchy B.K., Sarafoff M., Kerler R., Rabes H.M.
Amplification, rearrangements, and enhanced expression of c-myc in chemically induced rat liver tumors in vivo and in vitro.
Cancer Res. 49:6781-6787(1989)

CLPUB00363
Kerler R.
In vivo rats liver cells induced by chemical carcinogens in vitro: establishment, cytogenetic and cell biology characterization of immortalized and neoplastically transformed cell lines.
Thesis PhD (2000); Ludwig Maximilians University of Munich; Munich; Germany

Cross-references
Cell line collections (Providers) DSMZ; ACC-623
Cell line databases/resources DSMZCellDive; ACC-623
Encyclopedic resources Wikidata; Q54813486
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number13