ID   CL-50IIa
AC   CVCL_1985
SY   CL 50-IIa; CL50IIa
DR   DSMZ; ACC-623
DR   DSMZCellDive; ACC-623
DR   Wikidata; Q54813486
RX   CelloPub=CLPUB00363;
RX   PubMed=2684400;
RX   PubMed=2895109;
CC   Doubling time: ~50-60 hours (DSMZ=ACC-623).
CC   Transformant: ChEBI; CHEBI_34873; N-nitrosodiethylamine (Diethylnitrosamine; DEN).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: Wistar-AF/Han.
DI   NCIt; C60416; Rat hepatocellular carcinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_WU98 ! CL-50
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
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RX   CelloPub=CLPUB00363;
RA   Kerler R.;
RT   "In vivo rats liver cells induced by chemical carcinogens in vitro:
RT   establishment, cytogenetic and cell biology characterization of
RT   immortalized and neoplastically transformed cell lines.";
RL   Thesis PhD (2000); Ludwig Maximilians University of Munich; Munich; Germany.
//
RX   PubMed=2684400;
RA   Suchy B.K., Sarafoff M., Kerler R., Rabes H.M.;
RT   "Amplification, rearrangements, and enhanced expression of c-myc in
RT   chemically induced rat liver tumors in vivo and in vitro.";
RL   Cancer Res. 49:6781-6787(1989).
//
RX   PubMed=2895109; DOI=10.1007/BF00417823;
RA   Kerler R., Rabes H.M.;
RT   "Preneoplastic rat liver cells in vitro: slow progression without
RT   promoters, hormones, or growth factors.";
RL   J. Cancer Res. Clin. Oncol. 114:113-123(1988).
//