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Cellosaurus Vero-B4 (CVCL_1912)

[Text version]
Cell line name Vero-B4
Synonyms VERO-B4; Vero B4; VeroB4
Accession CVCL_1912
Resource Identification Initiative To cite this cell line use: Vero-B4 (RRID:CVCL_1912)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Virology: Susceptible to infection by Middle East respiratory syndrome-related coronavirus (MERS-CoV) (PubMed=25531820).
Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=34339474).
Doubling time: ~25 hours (DSMZ=ACC-33).
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=25531820; DOI=10.3201/eid2101.141342
Meyer B., Garcia-Bocanegra I., Wernery U., Wernery R., Sieberg A., Muller M.A., Drexler J.F., Drosten C., Eckerle I.
Serologic assessment of possibility for MERS-CoV infection in equids.
Emerg. Infect. Dis. 21:181-182(2015)

PubMed=34339474; DOI=10.1371/journal.pone.0255622
Pommerenke C., Rand U., Uphoff C.C., Nagel S., Zaborski M., Hauer V., Kaufmann M., Meyer C., Denkmann S.A., Riese P., Eschke K., Kim Y., Safranko Z.M., Kurolt I.-C., Markotic A., Cicin-Sain L., Steenpass L.
Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies.
PLoS ONE 16:E0255622-E0255622(2021)

Cell line collections (Providers) CCLV; CCLV-RIE 0929
Cell line databases/resources CLO; CLO_0009528
CLDB; cl4659
DSMZCellDive; ACC-33
Encyclopedic resources Wikidata; Q54993054
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20