ID   Vero-B4
AC   CVCL_1912
SY   VERO-B4; Vero B4; VeroB4
DR   CLO; CLO_0009528
DR   CLDB; cl4659
DR   CCLV; CCLV-RIE 0929
DR   CCLV; CCLV-RIE 1146
DR   DSMZ; ACC-33
DR   DSMZCellDive; ACC-33
DR   Wikidata; Q54993054
RX   PubMed=25531820;
RX   PubMed=34339474;
CC   Group: Non-human primate cell line.
CC   Group: Vaccine production cell line.
CC   Virology: Susceptible to infection by Middle East respiratory syndrome-related coronavirus (MERS-CoV) (PubMed=25531820).
CC   Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=34339474).
CC   Doubling time: ~25 hours (DSMZ=ACC-33).
CC   Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=60711; ! Chlorocebus sabaeus (Green monkey)
HI   CVCL_0059 ! Vero
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
//
RX   PubMed=25531820; DOI=10.3201/eid2101.141342; PMCID=PMC4285277;
RA   Meyer B., Garcia-Bocanegra I., Wernery U., Wernery R., Sieberg A.,
RA   Muller M.A., Drexler J.F., Drosten C., Eckerle I.;
RT   "Serologic assessment of possibility for MERS-CoV infection in
RT   equids.";
RL   Emerg. Infect. Dis. 21:181-182(2015).
//
RX   PubMed=34339474; DOI=10.1371/journal.pone.0255622; PMCID=PMC8328321;
RA   Pommerenke C., Rand U., Uphoff C.C., Nagel S., Zaborski M., Hauer V.,
RA   Kaufmann M., Meyer C., Denkmann S.A., Riese P., Eschke K., Kim Y.,
RA   Safranko Z.M., Kurolt I.-C., Markotic A., Cicin-Sain L., Steenpass L.;
RT   "Identification of cell lines CL-14, CL-40 and CAL-51 as suitable
RT   models for SARS-CoV-2 infection studies.";
RL   PLoS ONE 16:E0255622-E0255622(2021).
//