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Cellosaurus PaCaDD-137 (CVCL_1850)

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Cell line name PaCaDD-137
Synonyms PACADD-137; PACADD137
Accession CVCL_1850
Resource Identification Initiative To cite this cell line use: PaCaDD-137 (RRID:CVCL_1850)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 24.24 hours (PubMed=21683373); ~2-3 days (DSMZ=ACC-711).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Pancreas, head; UBERON=UBERON_0001069.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (DepMap=ACH-001377).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (DepMap=ACH-001377).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001377; DSMZ=ACC-711

Markers:
AmelogeninX
CSF1PO11,12
D2S133818,19
D3S135815,16
D5S8189,12
D7S8209,10
D8S117910 (DSMZ=ACC-711)
10,12 (DepMap=ACH-001377)
D13S31711
D16S53911,12
D18S5114
D19S43312,13
D21S1129.2,32.2
FGA25,26
Penta D9,11
Penta E12,17
TH019,9.3
TPOX8
vWA18,19 (DSMZ=ACC-711)
18,19,20 (DepMap=ACH-001377)

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Publications

PubMed=21683373; DOI=10.1016/j.jss.2011.04.021
Felix Ruckert, Daniela Aust, Iris Bohme, Kristin Werner, Aljoscha Brandt, Eleftherios Phedias Diamandis, Christian Krautz, Sandra Hering, Hans-Detlev Saeger, Robert Grutzmann, Christian Pilarsky;
Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method.
J. Surg. Res. 172:29-39(2012)

DOI=10.4172/2324-9293.1000104
Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger;
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) DSMZ; ACC-711
Cell line databases/resources cancercelllines; CVCL_1850
Cell_Model_Passport; SIDM01352
DepMap; ACH-001377
DSMZCellDive; ACC-711
Encyclopedic resources Wikidata; Q54937423
Polymorphism and mutation databases Cosmic; 1559066
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23