ID   PaCaDD-137
AC   CVCL_1850
SY   PACADD-137; PACADD137
DR   cancercelllines; CVCL_1850
DR   Cell_Model_Passport; SIDM01352
DR   Cosmic; 1559066
DR   DepMap; ACH-001377
DR   DSMZ; ACC-711
DR   DSMZCellDive; ACC-711
DR   Wikidata; Q54937423
RX   DOI=10.4172/2324-9293.1000104;
RX   PubMed=21683373;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Caucasian.
CC   Doubling time: 24.24 hours (PubMed=21683373); ~2-3 days (DSMZ=ACC-711).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (DepMap=ACH-001377).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (DepMap=ACH-001377).
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: In situ; Pancreas, head; UBERON=UBERON_0001069.
ST   Source(s): DepMap=ACH-001377; DSMZ=ACC-711
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14
ST   D19S433: 12,13
ST   D21S11: 29.2,32.2
ST   D2S1338: 18,19
ST   D3S1358: 15,16
ST   D5S818: 9,12
ST   D7S820: 9,10
ST   D8S1179: 10 (DSMZ=ACC-711)
ST   D8S1179: 10,12 (DepMap=ACH-001377)
ST   FGA: 25,26
ST   Penta D: 9,11
ST   Penta E: 12,17
ST   TH01: 9,9.3
ST   TPOX: 8
ST   vWA: 18,19 (DSMZ=ACC-711)
ST   vWA: 18,19,20 (DepMap=ACH-001377)
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   75Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   DOI=10.4172/2324-9293.1000104;
RA   Wagenhauser, Markus Udo
RA   Ruckert, Felix
RA   Niedergethmann, Marco
RA   Grutzmann, Robert
RA   Saeger, Hans-Detlev
RT   "Distribution of characteristic mutations in native ductal
RT   adenocarcinoma of the pancreas and pancreatic cancer cell lines.";
RL   Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013).
//
RX   PubMed=21683373; DOI=10.1016/j.jss.2011.04.021;
RA   Ruckert, Felix
RA   Aust, Daniela
RA   Bohme, Iris
RA   Werner, Kristin
RA   Brandt, Aljoscha
RA   Diamandis, Eleftherios Phedias
RA   Krautz, Christian
RA   Hering, Sandra
RA   Saeger, Hans-Detlev
RA   Grutzmann, Robert
RA   Pilarsky, Christian
RT   "Five primary human pancreatic adenocarcinoma cell lines established
RT   by the outgrowth method.";
RL   J. Surg. Res. 172:29-39(2012).
//