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Cellosaurus EFM-192C (CVCL_1814)

[Text version]

Cell line name EFM-192C
Synonyms EFM192C
Accession CVCL_1814
Resource Identification Initiative To cite this cell line use: EFM-192C (RRID:CVCL_1814)
Comments Part of: GrayJW breast cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~4 days (DSMZ); 40.64 hours (https://www.synapse.org/#!Synapse:syn2347014).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,01:01
HLA-BB*07:02,39:01
HLA-CC*07:02,12:03
Class II
HLA-DQDQB1*06:13,06:13
HLA-DRDRB1*15:01,15:01
Disease Breast carcinoma (NCIt: C4872)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1812 ! EFM-192A
CVCL_1813 ! EFM-192B
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO12,13
D2S133817,25
D3S135814
D5S81812,13
D7S8208,11
D8S117910
D13S3179,14
D16S5398,13
D18S5117
D19S43314
D21S1132.2
FGA20
Penta D9
Penta E14,16
TH017
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
https://tcpaportal.org/mclp/
Publications

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y.-L., Mills G.B., Cho R.J., Collisson E.A., van 't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-311
Cell line databases/resources CLO; CLO_0002891
Cell_Model_Passport; SIDM01053
DSMZCellDive; ACC-311
LINCS_HMS; 51116
LINCS_LDP; LCL-1479
Chemistry resources PharmacoDB; EFM192C_324_2019
Encyclopedic resources Wikidata; Q54832054
Experimental variables resources EFO; EFO_0006570
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1172952
GEO; GSM1172860
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001002554
Entry history
Entry creation04-Apr-2012
Last entry update23-Jun-2022
Version number24