Cellosaurus cell line EFM-192B (CVCL

Cellosaurus EFM-192B (CVCL_1813)

[Text version]

Cell line name

EFM-192B

Synonyms

EFM192B

Accession

CVCL_1813

Resource Identification Initiative

To cite this cell line use: EFM-192B (RRID:CVCL_1813)

Comments

Part of: JWGray breast cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~4-5 days (DSMZ=ACC-308); 68.47 hours (JWGray panel).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

HLA typing

Source: PubMed=25960936

Class I
HLA-A	A*01:01,24:02
HLA-B	B*07:02,39:01
HLA-C	C*07:02,12:03
Class II
HLA-DQ	DQB1*06:02,02:02
HLA-DR	DRB1*15:01,09:10

Source: PubMed=26589293

Class I
HLA-A	A*01:01,24:02
HLA-B	B*07:02,39:01
HLA-C	C*07:02,12:03

Disease

Breast carcinoma (NCIt: C4872)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_1812 ! EFM-192A
CVCL_1814 ! EFM-192C

Sex of cell

Female

Age at sampling

46Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-308

Markers:

Amelogenin	X
CSF1PO	12,13
D2S1338	17,25
D3S1358	14,16
D5S818	12,13
D7S820	8,11
D8S1179	10
D13S317	9,14
D16S539	8,13
D18S51	17
D19S433	14
D21S11	32.2
FGA	20,22
Penta D	9
Penta E	14,16
TH01	7
TPOX	8,10
vWA	16

Web pages

Info; MCLP; -; https://tcpaportal.org/mclp/
Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255

Publications

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590
Anneleen Daemen, Obi L. Griffith, Laura M. Heiser, Nicholas J. Wang, Oana M. Enache, Zachary Sanborn, Francois Pepin, Steffen Durinck, James E. Korkola, Malachi Griffith, Joe S. Hur ...Show all 27 authors... , Nam Huh, Jongsuk Chung, Leslie Cope, Mary Jo Fackler, Christopher Benedict Umbricht, Saraswati Sukumar, Pankaj Seth, Vikas P. Sukhatme, Lakshmi R. Jakkula, Yi-Ling Lu, Gordon B. Mills, Raymond J. Cho, Eric A. Collisson, Laura J. van 't Veer, Paul T. Spellman, Joe W. Gray; Show fewer authors
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Sebastian Boegel, Martin Lower, Thomas Bukur, Ugur Sahin, John C. Castle;
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-308

Cell line databases/resources

CLO; CLO_0002890
Cell_Model_Passport; SIDM01054
DSMZCellDive; ACC-308
LINCS_HMS; 51115
LINCS_LDP; LCL-1312

Chemistry resources

PharmacoDB; EFM192B_323_2019

Encyclopedic resources

Wikidata; Q54832053

Experimental variables resources

EFO; EFO_0006569

Gene expression databases

ArrayExpress; E-MTAB-2706
GEO; GSM1172859
GEO; GSM1172951

Sequence databases

EGA; EGAS00001000610

Entry history

Entry creation

04-Apr-2012

Last entry update

10-Apr-2025

Version number