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Cellosaurus QIMR-WIL (CVCL_1645)

[Text version]
Cell line name QIMR-WIL
Synonyms QIMRWIL; WIL
Accession CVCL_1645
Resource Identification Initiative To cite this cell line use: QIMR-WIL (RRID:CVCL_1645)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North0
East Asian, South0
South Asian0.26
European, North70.81
European, South28.92
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=910545

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S8207,10
D13S31712,13
D16S53912
TH017,8
TPOX8,9
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=4894385; DOI=10.1002/ijc.2910030619
John Hebden Pope, M.K. Horne, Walter Scott;
Transformation of foetal human leukocytes in vitro by filtrates of a human leukaemic cell line containing herpes-like virus.
Int. J. Cancer 3:857-866(1968)

PubMed=5246694; DOI=10.1038/icb.1968.171
John Hebden Pope;
Establishment of cell lines from Australian leukaemic patients: presence of a herpes-like virus.
Aust. J. Exp. Biol. Med. Sci. 46:643-645(1968)

PubMed=5248028; DOI=10.1002/ijc.2910030513
Graeme A. Tomkins;
Chromosome studies on cultured lymphoblast cell lines from cases of New Guinea Burkitt lymphoma, myeloblastic and lymphoblastic leukaemia and infectious mononucleosis.
Int. J. Cancer 3:644-653(1968)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) ECACC; 86030601
Cell line databases/resources CLO; CLO_0008680
CLDB; cl4042
cancercelllines; CVCL_1645
Cell_Model_Passport; SIDM00467
Cosmic-CLP; 910545
DepMap; ACH-002299
LINCS_LDP; LCL-1075
Chemistry resources ChEMBL-Cells; CHEMBL3308301
ChEMBL-Targets; CHEMBL2366337
GDSC; 910545
PharmacoDB; QIMRWIL_1281_2019
PubChem_Cell_line; CVCL_1645
Encyclopedic resources Wikidata; Q54948838
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670356
Polymorphism and mutation databases Cosmic; 910545
Cosmic; 2131557
IARC_TP53; 21280
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number35