ID   QIMR-WIL
AC   CVCL_1645
SY   QIMRWIL; WIL
DR   CLO; CLO_0008680
DR   CLDB; cl4042
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   cancercelllines; CVCL_1645
DR   Cell_Model_Passport; SIDM00467
DR   ChEMBL-Cells; CHEMBL3308301
DR   ChEMBL-Targets; CHEMBL2366337
DR   Cosmic; 910545
DR   Cosmic; 2131557
DR   Cosmic-CLP; 910545
DR   DepMap; ACH-002299
DR   ECACC; 86030601
DR   EGA; EGAS00001000978
DR   GDSC; 910545
DR   GEO; GSM1670356
DR   IARC_TP53; 21280
DR   LINCS_LDP; LCL-1075
DR   PharmacoDB; QIMRWIL_1281_2019
DR   PRIDE; PXD030304
DR   PubChem_Cell_line; CVCL_1645
DR   Wikidata; Q54948838
RX   PubMed=4894385;
RX   PubMed=5246694;
RX   PubMed=5248028;
RX   PubMed=20164919;
RX   PubMed=27397505;
RX   PubMed=30894373;
RX   PubMed=35839778;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Population: Caucasian.
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=0%; East Asian, South=0%; South Asian=0.26%; European, North=70.81%; European, South=28.92% (PubMed=30894373).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): Cosmic-CLP
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 12,13
ST   D16S539: 12
ST   D5S818: 11,12
ST   D7S820: 7,10
ST   TH01: 7,8
ST   TPOX: 8,9
ST   vWA: 14,16
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 33
//
RX   PubMed=4894385; DOI=10.1002/ijc.2910030619;
RA   Pope J.H., Horne M.K., Scott W.;
RT   "Transformation of foetal human leukocytes in vitro by filtrates of a
RT   human leukaemic cell line containing herpes-like virus.";
RL   Int. J. Cancer 3:857-866(1968).
//
RX   PubMed=5246694; DOI=10.1038/icb.1968.171;
RA   Pope J.H.;
RT   "Establishment of cell lines from Australian leukaemic patients:
RT   presence of a herpes-like virus.";
RL   Aust. J. Exp. Biol. Med. Sci. 46:643-645(1968).
//
RX   PubMed=5248028; DOI=10.1002/ijc.2910030513;
RA   Tomkins G.A.;
RT   "Chromosome studies on cultured lymphoblast cell lines from cases of
RT   New Guinea Burkitt lymphoma, myeloblastic and lymphoblastic leukaemia
RT   and infectious mononucleosis.";
RL   Int. J. Cancer 3:644-653(1968).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S.,
RA   Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P.,
RA   Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H.,
RA   Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010;
RA   Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N.,
RA   Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J.,
RA   Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L.,
RA   Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S.,
RA   Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B.,
RA   Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.;
RT   "Pan-cancer proteomic map of 949 human cell lines.";
RL   Cancer Cell 40:835-849.e8(2022).
//