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Cellosaurus Lu-134-B (CVCL_1388)

[Text version]
Cell line name Lu-134-B
Synonyms NCC-c-Lu-134-B-S; Lu-134-b; LU-134-B; LU-134B; Lu-134B; Lu134B
Accession CVCL_1388
Resource Identification Initiative To cite this cell line use: Lu-134-B (RRID:CVCL_1388)
Comments Population: Japanese.
Doubling time: 57 hours (PubMed=3022030; PubMed=6098504).
Omics: SNP array analysis.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Asp1029Tyr (c.3085G>T); Zygosity=Heterozygous (PubMed=19394761).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1387 ! Lu-134-A
Sex of cell Male
Age at sampling 80Y
Category Cancer cell line
STR profile Source(s): JCRB; RCB


Run an STR similarity search on this cell line

PubMed=6098504; DOI=10.20772/cancersci1959.75.12_1089
Terasaki T., Kameya T., Nakajima T., Tsumuraya M., Shimosato Y., Kato K., Ichinose H., Nagatsu T., Hasegawa T.
Interconversion of biological characteristics of small cell lung cancer depending on culture conditions.
Gann 75:1089-1099(1984)

Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y., Higuchi H., Uei Y.
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

PubMed=3022030; DOI=10.1093/oxfordjournals.jjco.a039144
Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S., Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn. J. Clin. Oncol. 16:203-212(1986)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

PubMed=19394761; DOI=10.1016/j.canlet.2009.03.038
Shibata T., Kokubu A., Tsuta K., Hirohashi S.
Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer.
Cancer Lett. 283:203-211(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cell line collections (Providers) JCRB; JCRB0169
JCRB; FDSC0038 - Discontinued
RCB; RCB0467
Cell line databases/resources CLO; CLO_0050029
cancercelllines; CVCL_1388
Cell_Model_Passport; SIDM00295
CGH-DB; 90-1
CGH-DB; 9060-4
Anatomy/cell type resources BTO; BTO:0005439
Encyclopedic resources Wikidata; Q54903192
Gene expression databases GEO; GSM827209
Polymorphism and mutation databases Cosmic; 1212194
Cosmic; 1571750
Progenetix; CVCL_1388
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24