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Cellosaurus Lu-134-B (CVCL_1388)

[Text version]
Cell line name Lu-134-B
Synonyms NCC-c-Lu-134-B-S; Lu-134-b; LU-134-B; LU-134B; Lu-134B; Lu134B
Accession CVCL_1388
Resource Identification Initiative To cite this cell line use: Lu-134-B (RRID:CVCL_1388)
Comments Population: Japanese.
Doubling time: 57 hours (PubMed=3022030; PubMed=6098504).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Asp1029Tyr (c.3085G>T); Zygosity=Heterozygous (PubMed=19394761).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1387 ! Lu-134-A
Sex of cell Male
Age at sampling 80Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB0169; RCB=RCB0467

Markers:
AmelogeninX
CSF1PO12
D5S81811
D7S82011
D13S3179
D16S5399
TH019
TPOX11
vWA17

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Publications

PubMed=6098504; DOI=10.20772/cancersci1959.75.12_1089
Takeo Terasaki, Toru Kameya, Takashi Nakajima, Masaru Tsumuraya, Yukio Shimosato, Kanefusa Kato, Hiroshi Ichinose, Toshiharu Nagatsu, Tomoko Hasegawa;
Interconversion of biological characteristics of small cell lung cancer depending on culture conditions.
Gann 75:1089-1099(1984)

DOI=10.5795/jjscc.24.451
Masaru Tsumuraya, Takashi Nakajima, Takeo Terasaki, Tetsuro Kodama, Yukio Shimosato, Hisaaki Higuchi, Yoshio Uei;
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

PubMed=3022030; DOI=10.1093/oxfordjournals.jjco.a039144
Takeo Terasaki, Yukio Shimosato, Takashi Nakajima, Masaru Tsumuraya, Shojiroh Morinaga, Setsuo Hirohashi, Ken Yamaguchi, Kanefusa Kato, Hiroshi Ichinose, Toshiharu Nagatsu;
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn. J. Clin. Oncol. 16:203-212(1986)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7; PMCID=PMC1850681
Sana Yokoi, Kohichiroh Yasui, Fumiko Saito-Ohara, Katsumi Koshikawa, Toshihiko Iizasa, Takehiko Fujisawa, Takeo Terasaki, Akira Horii, Takashi Takahashi, Setsuo Hirohashi, Johji Inazawa;
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

PubMed=19394761; DOI=10.1016/j.canlet.2009.03.038
Tatsuhiro Shibata, Akiko Kokubu, Koji Tsuta, Setsuo Hirohashi;
Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer.
Cancer Lett. 283:203-211(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) JCRB; FDSC0038 - Discontinued
JCRB; JCRB0169
RCB; RCB0467
Cell line databases/resources CLO; CLO_0050029
cancercelllines; CVCL_1388
Cell_Model_Passport; SIDM00295
CGH-DB; 90-1
CGH-DB; 9060-4
LINCS_LDP; LCL-1834
Anatomy/cell type resources BTO; BTO_0005439
Encyclopedic resources Wikidata; Q54903192
Gene expression databases GEO; GSM827209
Polymorphism and mutation databases Cosmic; 1212194
Cosmic; 1571750
Progenetix; CVCL_1388
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27