• Mutation; HGNC; HGNC:583; APC; Simple; p.Gln789Ter (c.2365C>T); ClinVar=VCV000092341; Zygosity=Heterozygous (PubMed=24755471; ATCC=CRL-2159; Cosmic-CLP=907794; DepMap=ACH-000985).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (PubMed=24755471; ATCC=CRL-2159; Cosmic-CLP=907794; DepMap=ACH-000985).
  
• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (PubMed=12068308; PubMed=20570890; PubMed=24755471; ATCC=CRL-2159; Cosmic-CLP=907794; DepMap=ACH-000985).
  
• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Cys105Valfs*8 (c.313delT); ClinVar=VCV000940879; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=907794; DepMap=ACH-000985).
  
• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys164Argfs*3 (c.491delA); ClinVar=VCV000189448; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=907794; DepMap=ACH-000985).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (PubMed=16418264; PubMed=24755471; Cosmic-CLP=907794; DepMap=ACH-000985).
  

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PubMed=11414198; DOI=10.1007/s004320000207
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PubMed=16854228; DOI=10.1186/1476-4598-5-29; PMCID=PMC1550420
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PubMed=18258742; DOI=10.1073/pnas.0712176105; PMCID=PMC2268141
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PubMed=19927377; DOI=10.1002/gcc.20730; PMCID=PMC2818350
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PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
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PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514
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PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
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PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
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PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849
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Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=23932154; DOI=10.1016/j.radonc.2013.06.032
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PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony Wilks Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor ...Show all 17 authors... , Jennifer L. Wilding, David C. Bicknell, Ian Philip Mark Tomlinson, Walter Fred Bodmer, John M. Mariadason, Oliver M. Sieber; Show fewer authors
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PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652
Glenn S. Cowley, Barbara A. Weir, Francisca Vazquez, Pablo Tamayo, Justine A. Scott, Scott Rusin, Alexandra East-Seletsky, Levi D. Ali, William F.J. Gerath, Sarah E. Pantel, Patrick Hall Lizotte ...Show all 40 authors... , Guo-Zhi Jiang, Jessica Hsiao, Aviad Tsherniak, Elizabeth Dwinell, Simon Aoyama, Michael Okamoto, William Harrington, Ellen T. Gelfand, Thomas M. Green, Mark J. Tomko, Shuba Gopal, Terence C. Wong, Hu-Bo Li, Sara Howell, Nicolas Stransky, Ted Liefeld, Dongkeun Jang, Jonathan Bistline, Barbara Hill Meyers, Scott Allen Armstrong, Kenneth Carl Anderson, Kimberly Stegmaier, Michael Reich, David Pellman, Jesse S. Boehm, Jill P. Mesirov, Todd Robert Golub, David E. Root, William Chun Hahn; Show fewer authors
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
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PubMed=25926053; DOI=10.1038/ncomms8002
Enzo Medico, Mariangela Russo, Gabriele Picco, Carlotta Cancelliere, Emanuele Valtorta, Giorgio Corti, Michela Buscarino, Claudio Isella, Simona Lamba, Barbara Martinoglio, Silvio Veronese ...Show all 19 authors... , Salvatore Siena, Andrea Sartore-Bianchi, Marco Beccuti, Marcella Mottolese, Michael Linnebacher, Francesca Cordero, Federica Di Nicolantonio, Alberto Bardelli; Show fewer authors
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PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
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PubMed=26537799; DOI=10.1074/mcp.M115.051235; PMCID=PMC4762531
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PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
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PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
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PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477
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PubMed=29101300; DOI=10.15252/msb.20177701; PMCID=PMC5731344
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PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051; PMCID=PMC6343826
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
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PubMed=30971826; DOI=10.1038/s41586-019-1103-9
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
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Nature 569:503-508(2019)

PubMed=31395879; DOI=10.1038/s41467-019-11415-2; PMCID=PMC6687785
Katharine Yu, Bin Chen, Dvir Aran, Joe Charalel, Christina Yau, Douglas M. Wolf, Laura J. van 't Veer, Atul Janardhan Butte, Ted Goldstein, Marina Sirota;
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
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PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254
David Paul Nusinow, John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald 3rd, Marian Kalocsay, Judit Jane-Valbuena, Ellen T. Gelfand, Devin K. Schweppe, Mark P. Jedrychowski, Javad Golji ...Show all 20 authors... , Dale A. Porter, Tomas Rejtar, Y. Karen Wang, Gregory V. Kryukov, Frank Stegmeier, Brian K. Erickson, Levi Alexander Garraway, William Raj Sellers, Steven P. Gygi; Show fewer authors
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
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Pan-cancer proteomic map of 949 human cell lines.
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