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Cellosaurus KP-N-SI9s (CVCL_1340)

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Cell line name KP-N-SI9s
Synonyms KP-N-SI9S; KPNSI9s; KPNSI9S; SI9s
Accession CVCL_1340
Resource Identification Initiative To cite this cell line use: KP-N-SI9s (RRID:CVCL_1340)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Characteristics: Substrate-adherent type (S-type) (PubMed=2019470).
Doubling time: ~49 hours (Note=Lot 12152017) (JCRB=IFO50433).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Misspelling: KP-N-S19s; Note=Occasionally.
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ala (c.35G>C); ClinVar=VCV000045122; Zygosity=Heterozygous (DepMap=ACH-000446).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North75.78
East Asian, South24.21
South Asian0
European, North0
European, South0
Disease Adrenal gland neuroblastoma (NCIt: C4827)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7910 (KP-N-SI(LA))
Sex of cell Male
Age at sampling 5Y
Category Cancer cell line
STR profile Source(s): JCRB=IFO50433

Markers:
AmelogeninX,Y
CSF1PO10
D5S81813
D7S8208,11
D13S31711,14
D16S5399,13
TH016
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=2019470; DOI=10.1002/ijc.2910480221
Tohru Sugimoto, Hisao Ueyama, Hajime Hosoi, Johji Inazawa, Taiji Kato, John T. Kemshead, Charles Patrick Reynolds, Allen M. Gown, Hiroshi Mine, Tadashi Sawada;
Alpha-smooth-muscle actin and desmin expressions in human neuroblastoma cell lines.
Int. J. Cancer 48:277-283(1991)

PubMed=11129446; DOI=10.1097/00019606-200012000-00007
Tohru Sugimoto, Hiroshi Mine, Yoshihiro Horii, Katsuhito Takahashi, Ryozo Nagai, Ryuichi Morishita, Mihiro Komada, Yujiro Asada, Tadashi Sawada;
Neuroblastoma cell lines showing smooth muscle cell phenotypes.
Diagn. Mol. Pathol. 9:221-228(2000)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) JCRB; IFO50433
Cell line databases/resources cancercelllines; CVCL_1340
Cell_Model_Passport; SIDM00016
DepMap; ACH-000446
Biological sample resources BioSample; SAMN03472791
BioSample; SAMN10987824
Chemistry resources PharmacoDB; KPNS19s_787_2019
Encyclopedic resources Wikidata; Q54900399
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770
GEO; GSM887240
GEO; GSM888314
GEO; GSM1670006
Polymorphism and mutation databases Cosmic; 907315
IARC_TP53; 21441
IARC_TP53; 30109
LiGeA; CCLE_193
Progenetix; CVCL_1340
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number30