• Mutation; HGNC; HGNC:583; APC; Simple; p.Arg168Ile (c.503G>T); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Leu665Ter (c.1994T>A); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1864Tyr (c.5591C>A); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Ile2167Ser (c.6500T>G); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.Asn2720Lys (c.8160T>G); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Arg1989Ter (c.5965C>T); ClinVar=VCV000225842; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:795; ATM; Simple; p.Glu277Ter (c.829G>T); ClinVar=VCV000234216; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg337Cys (c.1009C>T); ClinVar=VCV000127327; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala146Thr (c.436G>A); ClinVar=VCV000197243; Zygosity=Heterozygous (PubMed=16969076; PubMed=20570890; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Gln (c.389G>A); ClinVar=VCV000007829; Zygosity=Heterozygous (PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Phe341Val (c.1021T>G); ClinVar=VCV000495806; Zygosity=Heterozygous (PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:9884; RB1; Simple; p.Glu137Ter (c.409G>T); ClinVar=VCV000126810; Zygosity=Heterozygous (PubMed=17088437; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Ser276Leu (c.827C>T); ClinVar=VCV002097524; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Arg321Gln (c.962G>A); Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:6769; SMAD3; Simple; p.Ser266Leu (c.797C>T); ClinVar=VCV001417802; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Heterozygous (PubMed=9331090; PubMed=15900046; PubMed=17088437; PubMed=18277095; PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
  

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PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742
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PubMed=16969076; DOI=10.4161/cbt.5.8.3251; PMCID=PMC2714972
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PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832
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PubMed=18277095; DOI=10.4161/cbt.7.5.5712
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Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination.
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PubMed=19372543; DOI=10.1158/1535-7163.MCT-08-0921; PMCID=PMC4020356
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DNA fingerprinting of the NCI-60 cell line panel.
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PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
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PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514
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Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
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PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
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5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
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PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108
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PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017
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PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511
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Mass homozygotes accumulation in the NCI-60 cancer cell lines as compared to HapMap trios, and relation to fragile site location.
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PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665
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PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189
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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.
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PubMed=23856246; DOI=10.1158/0008-5472.CAN-12-3342; PMCID=PMC4893961
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Global proteome analysis of the NCI-60 cell line panel.
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The metabolic demands of cancer cells are coupled to their size and protein synthesis rates.
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Genomic determinants of protein abundance variation in colorectal cancer cells.
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Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
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Nature 568:511-516(2019)

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HTS384 NCI60: the next phase of the NCI60 screen.
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