ID   HCC2998
AC   CVCL_1266
SY   HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998
DR   BTO; BTO_0003322
DR   CLO; CLO_0009962
DR   EFO; EFO_0005370
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   BioGRID_ORCS_Cell_line; 872
DR   cancercelllines; CVCL_1266
DR   Cell_Model_Passport; SIDM00118
DR   ChEMBL-Cells; CHEMBL3308074
DR   ChEMBL-Targets; CHEMBL613855
DR   ColonAtlas; HCC2998
DR   Cosmic; 875899
DR   Cosmic; 905971
DR   Cosmic; 974245
DR   Cosmic; 1092599
DR   Cosmic; 1305352
DR   Cosmic; 1312337
DR   Cosmic; 1436017
DR   Cosmic; 1479602
DR   Cosmic; 1676741
DR   Cosmic; 1803942
DR   Cosmic; 1998441
DR   Cosmic; 2301977
DR   Cosmic; 2811049
DR   Cosmic-CLP; 905971
DR   DepMap; ACH-001081
DR   EGA; EGAS00001000978
DR   GDSC; 905971
DR   GEO; GSM2146
DR   GEO; GSM50187
DR   GEO; GSM50251
DR   GEO; GSM743442
DR   GEO; GSM750796
DR   GEO; GSM799330
DR   GEO; GSM799393
DR   GEO; GSM844550
DR   GEO; GSM844551
DR   GEO; GSM846354
DR   GEO; GSM1153401
DR   GEO; GSM1178115
DR   GEO; GSM1178116
DR   GEO; GSM1178117
DR   GEO; GSM1181249
DR   GEO; GSM1181265
DR   GEO; GSM1346873
DR   GEO; GSM1448169
DR   GEO; GSM1669856
DR   GEO; GSM2124654
DR   GEO; GSM2550000
DR   IARC_TP53; 18070
DR   IARC_TP53; 21115
DR   LINCS_LDP; LCL-1191
DR   NCI-DTP; HCC-2998
DR   PharmacoDB; HCC2998_497_2019
DR   PRIDE; PXD003539
DR   PRIDE; PXD005235
DR   PRIDE; PXD005942
DR   PRIDE; PXD005946
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1266
DR   PubChem_Cell_line; CVCL_1266
DR   SKY/M-FISH/CGH; 2794
DR   Wikidata; Q54881683
RX   PubMed=2041050;
RX   PubMed=3335022;
RX   PubMed=9331090;
RX   PubMed=10700174;
RX   PubMed=15748285;
RX   PubMed=15900046;
RX   PubMed=16969076;
RX   PubMed=17088437;
RX   PubMed=18277095;
RX   PubMed=19372543;
RX   PubMed=20164919;
RX   PubMed=20570890;
RX   PubMed=20606684;
RX   PubMed=22068913;
RX   PubMed=22336246;
RX   PubMed=22347499;
RX   PubMed=22384151;
RX   PubMed=22628656;
RX   PubMed=23856246;
RX   PubMed=23933261;
RX   PubMed=24279929;
RX   PubMed=24670534;
RX   PubMed=24755471;
RX   PubMed=25926053;
RX   PubMed=25944804;
RX   PubMed=27377824;
RX   PubMed=27397505;
RX   PubMed=27807467;
RX   PubMed=28179481;
RX   PubMed=28196595;
RX   PubMed=28683746;
RX   PubMed=28854368;
RX   PubMed=30894373;
RX   PubMed=30971826;
RX   PubMed=31733513;
RX   PubMed=35839778;
RX   PubMed=38861359;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
WW   Info; NCI DTP; NCI-60; https://dtp.cancer.gov/discovery_development/nci-60/cell_list.htm
WW   Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=16
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: JFCR39 cancer cell line panel.
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: NCI-60 cancer cell line panel.
CC   Population: Caucasian.
CC   Doubling time: 44.40 hours (PubMed=25944804); 31.5 hours (NCI-DTP=HCC-2998).
CC   HLA typing: A*02,24; B*37:01,40:06:01; C*04,06:02; DPB1*04:01; DQB1*03:01:01,05:02:01; DRB1*11,16 (PubMed=15748285).
CC   Microsatellite instability: Stable (MSS) (PubMed=24755471; PubMed=25926053; PubMed=28683746; Sanger).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg168Ile (c.503G>T); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Leu665Ter (c.1994T>A); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1450Ter (c.4348C>T); ClinVar=VCV000194585; Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Ser1864Tyr (c.5591C>A); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Ile2167Ser (c.6500T>G); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Asn2720Lys (c.8160T>G); Zygosity=Heterozygous (PubMed=17088437; PubMed=24755471; PubMed=28179481; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Arg1989Ter (c.5965C>T); ClinVar=VCV000225842; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Glu277Ter (c.829G>T); ClinVar=VCV000234216; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg337Cys (c.1009C>T); ClinVar=VCV000127327; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Ala146Thr (c.436G>A); ClinVar=VCV000197243; Zygosity=Heterozygous (PubMed=16969076; PubMed=20570890; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Gln (c.389G>A); ClinVar=VCV000007829; Zygosity=Heterozygous (PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Phe341Val (c.1021T>G); ClinVar=VCV000495806; Zygosity=Heterozygous (PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Glu137Ter (c.409G>T); ClinVar=VCV000126810; Zygosity=Heterozygous (PubMed=17088437; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Ser276Leu (c.827C>T); ClinVar=VCV002097524; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Arg321Gln (c.962G>A); Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:6769; SMAD3; Simple; p.Ser266Leu (c.797C>T); ClinVar=VCV001417802; Zygosity=Heterozygous (PubMed=24755471; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Heterozygous (PubMed=9331090; PubMed=15900046; PubMed=17088437; PubMed=18277095; PubMed=24755471; PubMed=28683746; Cosmic-CLP=905971; DepMap=ACH-001081).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Metabolomics.
CC   Omics: Phenotyping; CRISPR screening.
CC   Omics: Phenotyping; Drug screening.
CC   Omics: Phenotyping; Fluorescent probe library screening.
CC   Omics: Proteomics.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Proteomics; PTM; Phosphorylation; Quantitative.
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; lncRNA profiling; RT-qPCR platform.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Genome ancestry: African=1.41%; Native American=0%; East Asian, North=0%; East Asian, South=1.46%; South Asian=8.24%; European, North=35.72%; European, South=53.15% (PubMed=30894373).
ST   Source(s): Cosmic-CLP=905971; PubMed=19372543; PubMed=25926053
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 11,12
ST   D16S539: 9,12
ST   D18S51: 12,15
ST   D19S433: 12,15
ST   D21S11: 29,30
ST   D2S1338: 18,23
ST   D3S1358: 17,19
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 11,14
ST   FGA: 25
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 18,19
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 27-11-25; Version: 46
//
RX   PubMed=22347499; DOI=10.1371/journal.pone.0031628; PMCID=PMC3276511;
RA   Ruan, Xiao-Yang
RA   Kocher, Jean-Pierre A.
RA   Pommier, Yves
RA   Liu, Hong-Fang
RA   Reinhold, William C.
RT   "Mass homozygotes accumulation in the NCI-60 cancer cell lines as
RT   compared to HapMap trios, and relation to fragile site location.";
RL   PLoS ONE 7:e31628.1-e31628.9(2012).
//
RX   PubMed=15748285; DOI=10.1186/1479-5876-3-11; PMCID=PMC555742;
RA   Adams, Sharon
RA   Robbins, Fu-Meei
RA   Chen, Deborah
RA   Wagage, Devika
RA   Holbeck, Susan L.
RA   Morse, Herbert Carpenter 3rd
RA   Stroncek, David
RA   Marincola, Francesco M.
RT   "HLA class I and II genotype of the NCI-60 cell lines.";
RL   J. Transl. Med. 3:11.1-11.8(2005).
//
RX   PubMed=17088437; DOI=10.1158/1535-7163.MCT-06-0433; PMCID=PMC2705832;
RA   Ikediobi, Ogechi N.
RA   Davies, Helen R.
RA   Bignell, Graham Robert
RA   Edkins, Sarah
RA   Stevens, Claire
RA   O'Meara, Sarah
RA   Santarius, Thomas
RA   Avis, Tim
RA   Barthorpe, Syd
RA   Brackenbury, Lisa
RA   Buck, Gemma
RA   Butler, Adam P.
RA   Clements, Jody
RA   Cole, Jennifer
RA   Dicks, Ed
RA   Forbes, Simon
RA   Gray, Kristian
RA   Halliday, Kelly
RA   Harrison, Rachel
RA   Hills, Katy
RA   Hinton, Jonathan
RA   Hunter, Chris
RA   Jenkinson, Andy
RA   Jones, David
RA   Kosmidou, Vivian
RA   Lugg, Richard
RA   Menzies, Andrew
RA   Mironenko, Tatiana
RA   Parker, Adrian
RA   Perry, Janet
RA   Raine, Keiran Martin
RA   Richardson, David
RA   Shepherd, Rebecca
RA   Small, Alex
RA   Smith, Raffaella
RA   Solomon, Helen
RA   Stephens, Philip J.
RA   Teague, Jon W.
RA   Tofts, Calli
RA   Varian, Jennifer
RA   Webb, Tony
RA   West, Sofie
RA   Widaa, Sara
RA   Yates, Andy
RA   Reinhold, William C.
RA   Weinstein, John N.
RA   Stratton, Michael Rudolf
RA   Futreal, P. Andrew
RA   Wooster, Richard
RT   "Mutation analysis of 24 known cancer genes in the NCI-60 cell line
RT   set.";
RL   Mol. Cancer Ther. 5:2606-2612(2006).
//
RX   PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028;
RA   Bracht, Karin
RA   Nicholls, Angela M.
RA   Liu, Ying
RA   Bodmer, Walter Fred
RT   "5-fluorouracil response in a large panel of colorectal cancer cell
RT   lines is associated with mismatch repair deficiency.";
RL   Br. J. Cancer 103:340-346(2010).
//
RX   PubMed=22628656; DOI=10.1126/science.1218595; PMCID=PMC3526189;
RA   Jain, Mohit
RA   Nilsson, Roland
RA   Sharma, Sonia
RA   Madhusudhan, Nikhil
RA   Kitami, Toshimori
RA   Souza, Amanda L.
RA   Kafri, Ran
RA   Kirschner, Marc Wallace
RA   Clish, Clary B.
RA   Mootha, Vamsi Krishna
RT   "Metabolite profiling identifies a key role for glycine in rapid
RT   cancer cell proliferation.";
RL   Science 336:1040-1044(2012).
//
RX   PubMed=2041050; DOI=10.1093/jnci/83.11.757;
RA   Monks, Anne
RA   Scudiero, Dominic A.
RA   Skehan, Philip
RA   Shoemaker, Robert H.
RA   Paull, Kenneth D.
RA   Vistica, David T.
RA   Hose, Curtis D.
RA   Langley, John
RA   Cronise, Paul
RA   Vaigro-Wolff, Anne
RA   Gray-Goodrich, Marcia
RA   Campbell, Hugh
RA   Mayo, Joseph G.
RA   Boyd, Michael R.
RT   "Feasibility of a high-flux anticancer drug screen using a diverse
RT   panel of cultured human tumor cell lines.";
RL   J. Natl. Cancer Inst. 83:757-766(1991).
//
RX   PubMed=24670534; DOI=10.1371/journal.pone.0092047; PMCID=PMC3966786;
RA   Varma, Sudhir
RA   Pommier, Yves
RA   Sunshine, Margot
RA   Weinstein, John N.
RA   Reinhold, William C.
RT   "High resolution copy number variation data in the NCI-60 cancer cell
RT   lines from whole genome microarrays accessible through CellMiner.";
RL   PLoS ONE 9:e92047.1-e92047.15(2014).
//
RX   PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775;
RA   Goncalves, Emanuel
RA   Poulos, Rebecca C.
RA   Cai, Zhao-Xiang
RA   Barthorpe, Syd
RA   Manda, Srikanth S.
RA   Lucas, Natasha
RA   Beck, Alexandra
RA   Bucio-Noble, Daniel
RA   Dausmann, Michael
RA   Hall, Caitlin
RA   Hecker, Michael
RA   Koh, Jennifer
RA   Lightfoot, Howard
RA   Mahboob, Sadia
RA   Mali, Iman
RA   Morris, James
RA   Richardson, Laura
RA   Seneviratne, Akila J.
RA   Shepherd, Rebecca
RA   Sykes, Erin
RA   Thomas, Frances
RA   Valentini, Sara
RA   Williams, Steven G.
RA   Wu, Yang-Xiu
RA   Xavier, Dylan
RA   MacKenzie, Karen L.
RA   Hains, Peter G.
RA   Tully, Brett
RA   Robinson, Phillip James
RA   Zhong, Qing
RA   Garnett, Mathew J.
RA   Reddel, Roger Robert
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RL   Cancer Cell 40:835-849.e8(2022).
//
RX   PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017;
RA   Kong, De-Xin
RA   Yamori, Takao
RT   "JFCR39, a panel of 39 human cancer cell lines, and its application in
RT   the discovery and development of anticancer drugs.";
RL   Bioorg. Med. Chem. 20:1947-1951(2012).
//
RX   PubMed=28854368; DOI=10.1016/j.celrep.2017.08.010; PMCID=PMC5583477;
RA   Roumeliotis, Theodoros I.
RA   Williams, Steven P.
RA   Goncalves, Emanuel
RA   Alsinet, Clara
RA   Del Castillo Velasco-Herrera, Martin
RA   Aben, Nanne
RA   Ghavidel, Fatemeh Zamanzad
RA   Michaut, Magali
RA   Schubert, Michael
RA   Price, Stacey
RA   Wright, James C.
RA   Yu, Lu
RA   Yang, Mi
RA   Dienstmann, Rodrigo
RA   Guinney, Justin H.
RA   Beltrao, Pedro
RA   Brazma, Alvis
RA   Pardo, Mercedes
RA   Stegle, Oliver
RA   Adams, David J.
RA   Wessels, Lodewyk F.A.
RA   Saez-Rodriguez, Julio
RA   McDermott, Ultan
RA   Choudhary, Jyoti S.
RT   "Genomic determinants of protein abundance variation in colorectal
RT   cancer cells.";
RL   Cell Rep. 20:2201-2214(2017).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico, Enzo
RA   Russo, Mariangela
RA   Picco, Gabriele
RA   Cancelliere, Carlotta
RA   Valtorta, Emanuele
RA   Corti, Giorgio
RA   Buscarino, Michela
RA   Isella, Claudio
RA   Lamba, Simona
RA   Martinoglio, Barbara
RA   Veronese, Silvio
RA   Siena, Salvatore
RA   Sartore-Bianchi, Andrea
RA   Beccuti, Marco
RA   Mottolese, Marcella
RA   Linnebacher, Michael
RA   Cordero, Francesca
RA   Di Nicolantonio, Federica
RA   Bardelli, Alberto
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//
RX   PubMed=22068913; DOI=10.1073/pnas.1111840108; PMCID=PMC3219108;
RA   Gillet, Jean-Pierre
RA   Calcagno, Anna Maria
RA   Varma, Sudhir
RA   Marino, Miguel
RA   Green, Lisa J.
RA   Vora, Meena I.
RA   Patel, Chirayu
RA   Orina, Josiah N.
RA   Eliseeva, Tatiana A.
RA   Singal, Vineet
RA   Padmanabhan, Raji
RA   Davidson, Ben
RA   Ganapathi, Ram
RA   Sood, Anil K.
RA   Rueda, Bo R.
RA   Ambudkar, Suresh V.
RA   Gottesman, Michael Marc
RT   "Redefining the relevance of established cancer cell lines to the
RT   study of mechanisms of clinical anti-cancer drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:18708-18713(2011).
//
RX   PubMed=22384151; DOI=10.1371/journal.pone.0032096; PMCID=PMC3285665;
RA   Lee, Jun-Seok
RA   Kim, Yun Kyung
RA   Kim, Han Jo
RA   Hajar, Siti
RA   Tan, Yee Ling
RA   Kang, Nam-Young
RA   Ng, Shin Hui
RA   Yoon, Chang No
RA   Chang, Young-Tae
RT   "Identification of cancer cell-line origins using fluorescence
RT   image-based phenomic screening.";
RL   PLoS ONE 7:e32096.1-e32096.8(2012).
//
RX   PubMed=30971826; DOI=10.1038/s41586-019-1103-9;
RA   Behan, Fiona M.
RA   Iorio, Francesco
RA   Picco, Gabriele
RA   Goncalves, Emanuel
RA   Beaver, Charlotte M.
RA   Migliardi, Giorgia
RA   Santos, Rita
RA   Rao, Yanhua
RA   Sassi, Francesco
RA   Pinnelli, Marika
RA   Ansari, Rizwan
RA   Harper, Sarah
RA   Jackson, David Adam
RA   McRae, Rebecca
RA   Pooley, Rachel
RA   Wilkinson, Piers
RA   van der Meer, Dieudonne J.
RA   Dow, David
RA   Buser-Doepner, Carolyn A.
RA   Bertotti, Andrea
RA   Trusolino, Livio
RA   Stronach, Euan Alexander
RA   Saez-Rodriguez, Julio
RA   Yusa, Kosuke
RA   Garnett, Mathew J.
RT   "Prioritization of cancer therapeutic targets using CRISPR-Cas9
RT   screens.";
RL   Nature 568:511-516(2019).
//
RX   PubMed=3335022;
RA   Alley, Michael Curtis
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Hursey, Miriam L.
RA   Czerwinski, Maciej J.
RA   Fine, Donald L.
RA   Abbott, Betty Jane
RA   Mayo, Joseph G.
RA   Shoemaker, Robert H.
RA   Boyd, Michael R.
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=10700174; DOI=10.1038/73432;
RA   Ross, Douglas T.
RA   Scherf, Uwe
RA   Eisen, Michael Bruce
RA   Perou, Charles M.
RA   Rees, Christian
RA   Spellman, Paul T.
RA   Iyer, Vishwanath R.
RA   Jeffrey, Stefanie S.
RA   van de Rijn, Matt
RA   Waltham, Mark C.
RA   Pergamenschikov, Alexander
RA   Lee, Jeffrey C.F.
RA   Lashkari, Deval
RA   Shalon, Dari
RA   Myers, Timothy Gene
RA   Weinstein, John N.
RA   Botstein, David
RA   Brown, Patrick O'Reilly
RT   "Systematic variation in gene expression patterns in human cancer cell
RT   lines.";
RL   Nat. Genet. 24:227-235(2000).
//
RX   PubMed=9331090;
RA   O'Connor, Patrick M.
RA   Jackman, Joany
RA   Bae, Insoo
RA   Myers, Timothy Gene
RA   Fan, Sai-Jun
RA   Mutoh, Masato
RA   Scudiero, Dominic A.
RA   Monks, Anne
RA   Sausville, Edward A.
RA   Weinstein, John N.
RA   Friend, Stephen H.
RA   Fornace, Albert J. Jr.
RA   Kohn, Kurt W.
RT   "Characterization of the p53 tumor suppressor pathway in cell lines of
RT   the National Cancer Institute anticancer drug screen and correlations
RT   with the growth-inhibitory potency of 123 anticancer agents.";
RL   Cancer Res. 57:4285-4300(1997).
//
RX   PubMed=24279929; DOI=10.1186/2049-3002-1-20; PMCID=PMC4178206;
RA   Dolfi, Sonia C.
RA   Chan, Leo Li-Ying
RA   Qiu, Jean
RA   Tedeschi, Philip M.
RA   Bertino, Joseph Rocco
RA   Hirshfield, Kim Marie
RA   Oltvai, Zoltan Nagy
RA   Vazquez, Alexei
RT   "The metabolic demands of cancer cells are coupled to their size and
RT   protein synthesis rates.";
RL   Cancer Metab. 1:20.1-20.13(2013).
//
RX   PubMed=15900046; DOI=10.1093/jnci/dji133;
RA   Mashima, Tetsuo
RA   Oh-hara, Tomoko
RA   Sato, Shigeo
RA   Mochizuki, Mikiko
RA   Sugimoto, Yoshikazu
RA   Yamazaki, Kanami
RA   Hamada, Jun-ichi
RA   Tada, Mitsuhiro
RA   Moriuchi, Tetsuya
RA   Ishikawa, Yuichi
RA   Kato, Yo
RA   Tomoda, Hiroshi
RA   Yamori, Takao
RA   Tsuruo, Takashi
RT   "p53-defective tumors with a functional apoptosome-mediated pathway: a
RT   new therapeutic target.";
RL   J. Natl. Cancer Inst. 97:765-777(2005).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
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RA   von Euw, Erika Maria
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RT   arrays.";
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RA   Zeng, Zhao-Shi
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RT   human cancer.";
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RA   Menden, Michael Patrick
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RA   Mouradov, Dmitri
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RA   Tanaka, Noritaka
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RA   Zampella, John G.
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RA   Berglind, Hanna
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RA   Ishioka, Chikashi
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RT   paradigm for cell line cross-contamination.";
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RT   "Global proteome analysis of the NCI-60 cell line panel.";
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RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil, Julie
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//