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Cellosaurus D384 Med (CVCL_1157)

[Text version]
Cell line name D384 Med
Synonyms D-384 Med; D-384 Med-C; D-384MED; D384Med; Med 384; H384
Accession CVCL_1157
Resource Identification Initiative To cite this cell line use: D384 Med (RRID:CVCL_1157)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 2.44 days (PubMed=1904513).
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Misspelling: D384MG; Cosmic=1175809.
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Disease Medulloblastoma, non-WNT/non-SHH, group 3 (NCIt: C129445)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y5M
Category Cancer cell line
Publications

PubMed=2180567
Sandra H. Bigner, Henry Seth Friedman, Bert Vogelstein, W. Jerry Oakes, Darell Doty Bigner;
Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts.
Cancer Res. 50:2347-2350(1990)

PubMed=1822845
Carol J. Wikstrand, Henry Seth Friedman, Darell Doty Bigner;
Medulloblastoma cell-substrate interaction in vitro.
Invasion Metastasis 11:310-324(1991)

PubMed=1904513
Xuan-Min He, Carol J. Wikstrand, Henry Seth Friedman, Sandra H. Bigner, Samuel J. Pleasure, John Quinn Trojanowski, Darell Doty Bigner;
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
Lab. Invest. 64:833-843(1991)

DOI=10.1007/0-306-46861-1_11
Francis Ali-Osman;
Brain tumors.
(In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20847082; DOI=10.1093/neuonc/noq091; PMCID=PMC3018940
Natalia Teider, Deborah K. Scott, Adrianne Neiss, Shyamal Dilhan Weeraratne, Vladimir M. Amani, Yi-Fei Wang, Victor E. Marquez, Yoon-Jae Cho, Scott L. Pomeroy;
Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.
Neuro-oncol. 12:1244-1256(2010)

PubMed=21177782; DOI=10.1093/neuonc/noq179; PMCID=PMC3064629
Shyamal Dilhan Weeraratne, Vladimir M. Amani, Adrianne Neiss, Natalia Teider, Deborah K. Scott, Scott L. Pomeroy, Yoon-Jae Cho;
miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma.
Neuro-oncol. 13:165-175(2011)

PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Delyan P. Ivanov, Beth Coyle, David A. Walker, Anna M. Grabowska;
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)

PubMed=27812533; DOI=10.1016/j.dib.2016.10.004; PMCID=PMC5079239
Delyan P. Ivanov, David A. Walker, Beth Coyle, Anna M. Grabowska;
Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1157
Cell_Model_Passport; SIDM01856
DepMap; ACH-001052
Encyclopedic resources Wikidata; Q54817222
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM482335
Polymorphism and mutation databases Cosmic; 946379
Cosmic; 1175809
IARC_TP53; 27690
Progenetix; CVCL_1157
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23