ID   D384 Med
AC   CVCL_1157
SY   D-384 Med; D-384 Med-C; D-384MED; D384Med; Med 384; H384
DR   ArrayExpress; E-MTAB-783
DR   cancercelllines; CVCL_1157
DR   Cell_Model_Passport; SIDM01856
DR   Cosmic; 946379
DR   Cosmic; 1175809
DR   DepMap; ACH-001052
DR   GEO; GSM482335
DR   IARC_TP53; 27690
DR   Progenetix; CVCL_1157
DR   Wikidata; Q54817222
RX   DOI=10.1007/0-306-46861-1_11;
RX   PubMed=1822845;
RX   PubMed=1904513;
RX   PubMed=2180567;
RX   PubMed=20164919;
RX   PubMed=20847082;
RX   PubMed=21177782;
RX   PubMed=27498314;
RX   PubMed=27812533;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: 2.44 days (PubMed=1904513).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Misspelling: D384MG; Cosmic=1175809.
CC   Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
DI   NCIt; C129445; Medulloblastoma, non-WNT/non-SHH, group 3
DI   ORDO; Orphanet_616; Medulloblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y5M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   DOI=10.1007/0-306-46861-1_11;
RA   Ali-Osman F.;
RT   "Brain tumors.";
RL   (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999).
//
RX   PubMed=1822845;
RA   Wikstrand C.J., Friedman H.S., Bigner D.D.;
RT   "Medulloblastoma cell-substrate interaction in vitro.";
RL   Invasion Metastasis 11:310-324(1991).
//
RX   PubMed=1904513;
RA   He X.-M., Wikstrand C.J., Friedman H.S., Bigner S.H., Pleasure S.J.,
RA   Trojanowski J.Q., Bigner D.D.;
RT   "Differentiation characteristics of newly established medulloblastoma
RT   cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable
RT   xenografts.";
RL   Lab. Invest. 64:833-843(1991).
//
RX   PubMed=2180567;
RA   Bigner S.H., Friedman H.S., Vogelstein B., Oakes W.J., Bigner D.D.;
RT   "Amplification of the c-myc gene in human medulloblastoma cell lines
RT   and xenografts.";
RL   Cancer Res. 50:2347-2350(1990).
//
RX   PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113;
RA   Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=20847082; DOI=10.1093/neuonc/noq091; PMCID=PMC3018940;
RA   Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F.,
RA   Marquez V.E., Cho Y.-J., Pomeroy S.L.;
RT   "Neuralized1 causes apoptosis and downregulates Notch target genes in
RT   medulloblastoma.";
RL   Neuro-oncol. 12:1244-1256(2010).
//
RX   PubMed=21177782; DOI=10.1093/neuonc/noq179; PMCID=PMC3064629;
RA   Weeraratne S.D., Amani V.M., Neiss A., Teider N., Scott D.K.,
RA   Pomeroy S.L., Cho Y.-J.;
RT   "miR-34a confers chemosensitivity through modulation of MAGE-A and p53
RT   in medulloblastoma.";
RL   Neuro-oncol. 13:165-175(2011).
//
RX   PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028;
RA   Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.;
RT   "In vitro models of medulloblastoma: choosing the right tool for the
RT   job.";
RL   J. Biotechnol. 236:10-25(2016).
//
RX   PubMed=27812533; DOI=10.1016/j.dib.2016.10.004; PMCID=PMC5079239;
RA   Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.;
RT   "Data on the number and frequency of scientific literature citations
RT   for established medulloblastoma cell lines.";
RL   Data Brief 9:696-698(2016).
//