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Cellosaurus 380 (CVCL_1047)

[Text version]
Cell line name 380
Accession CVCL_1047
Resource Identification Initiative To cite this cell line use: 380 (RRID:CVCL_1047)
Comments Doubling time: 3 days (PubMed=6334305); ~80 hours (DSMZ=ACC-39).
Omics: Deep quantitative proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133816,17
D3S135816,18
D5S81811,13
D7S8209,11
D8S117911,13
D13S31711,12
D16S53911,12
D18S5112,13
D19S43315,16
D21S1128,29
FGA19,20
Penta D10,13
Penta E9,11
TH016
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=6334305; DOI=10.1073/pnas.81.22.7166
Pegoraro L., Palumbo A., Erikson J., Falda M., Giovanazzo B., Emanuel B.S., Rovera G., Nowell P.C., Croce C.M.
A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.
Proc. Natl. Acad. Sci. U.S.A. 81:7166-7170(1984)

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=16809887; DOI=10.1159/000092345
Takenokuchi M., Saigo K., Nakamachi Y., Kawano S., Hashimoto M., Fujioka T., Koizumi T., Tatsumi E., Kumagai S.
Troglitazone inhibits cell growth and induces apoptosis of B-cell acute lymphoblastic leukemia cells with t(14;18).
Acta Haematol. 116:30-40(2006)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-39
ICLC; HTL99019
Cell line databases/resources CLO; CLO_0001007
CLDB; cl63
CLDB; cl4977
cancercelllines; CVCL_1047
DSMZCellDive; ACC-39
Biological sample resources BioSample; SAMN03473573
Encyclopedic resources Wikidata; Q54585241
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM119536
GEO; GSM236776
GEO; GSM236812
GEO; GSM1035325
GEO; GSM5137703
Polymorphism and mutation databases Cosmic; 924101
Cosmic; 1012056
Cosmic; 1130253
Cosmic; 1524787
Cosmic; 2804869
IARC_TP53; 27549
Progenetix; CVCL_1047
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number26