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Cellosaurus 380 (CVCL_1047)

[Text version]
Cell line name 380
Accession CVCL_1047
Resource Identification Initiative To cite this cell line use: 380 (RRID:CVCL_1047)
Comments Doubling time: 3 days (PubMed=6334305); ~80 hours (DSMZ=ACC-39).
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-39

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133816,17
D3S135816,18
D5S81811,13
D7S8209,11
D8S117911,13
D13S31711,12
D16S53911,12
D18S5112,13
D19S43315,16
D21S1128,29
FGA19,20
Penta D10,13
Penta E9,11
TH016
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=6334305; DOI=10.1073/pnas.81.22.7166; PMCID=PMC392098
Luigi Pegoraro, Antonio Palumbo, Jan Erikson, Michele Falda, Bruna Giovanazzo, Beverly S. Emanuel, Giovanni Rovera, Peter Carey Nowell, Carlo Maria Croce;
A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.
Proc. Natl. Acad. Sci. U.S.A. 81:7166-7170(1984)

PubMed=8108117
Thomas Albert, Birgit Urlbauer, Franz Kohlhuber, Bettina Hammersen, Dirk Eick;
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler;
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=16809887; DOI=10.1159/000092345
Mariko Takenokuchi, Katsuyasu Saigo, Yuji Nakamachi, Seiji Kawano, Makoto Hashimoto, Tsuyoshi Fujioka, Tamio Koizumi, Eiji Tatsumi, Shunichi Kumagai;
Troglitazone inhibits cell growth and induces apoptosis of B-cell acute lymphoblastic leukemia cells with t(14;18).
Acta Haematol. 116:30-40(2006)

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Graham Robert Bignell, Christopher D. Greenman, Helen R. Davies, Adam P. Butler, Sarah Edkins, Jenny M. Andrews, Gemma Buck, Lina Chen, David Beare, Calli Latimer, Sara Widaa ...Show all 22 authors... , Jonathan Hinton, Ciara Fahey, Bei-Yuan Fu, Sajani Swamy, Gillian L. Dalgliesh, Bin Tean Teh, Panos Deloukas, Feng-Tang Yang, Peter J. Campbell, P. Andrew Futreal, Michael Rudolf Stratton; Show fewer authors
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Hans Gunther Drexler, Sonja Eberth, Stefan Nagel, Roderick A.F. MacLeod;
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900
Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Paivi Ostling ...Show all 17 authors... , Olli-Pekka Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtio, Mattias Vesterlund, Rozbeh Jafari; Show fewer authors
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-39
ICLC; HTL99019
Cell line databases/resources CLO; CLO_0001007
CLDB; cl63
CLDB; cl4977
cancercelllines; CVCL_1047
DSMZCellDive; ACC-39
Biological sample resources BioSample; SAMN03473573
Encyclopedic resources Wikidata; Q54585241
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM119536
GEO; GSM236776
GEO; GSM236812
GEO; GSM1035325
GEO; GSM5137703
Polymorphism and mutation databases Cosmic; 924101
Cosmic; 1012056
Cosmic; 1130253
Cosmic; 1524787
Cosmic; 2804869
IARC_TP53; 27549
Progenetix; CVCL_1047
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28