ID   380
AC   CVCL_1047
DR   CLO; CLO_0001007
DR   CLDB; cl63
DR   CLDB; cl4977
DR   ArrayExpress; E-MTAB-783
DR   BioSample; SAMN03473573
DR   cancercelllines; CVCL_1047
DR   Cosmic; 924101
DR   Cosmic; 1012056
DR   Cosmic; 1130253
DR   Cosmic; 1524787
DR   Cosmic; 2804869
DR   DSMZ; ACC-39
DR   DSMZCellDive; ACC-39
DR   GEO; GSM119536
DR   GEO; GSM236776
DR   GEO; GSM236812
DR   GEO; GSM1035325
DR   GEO; GSM5137703
DR   IARC_TP53; 27549
DR   ICLC; HTL99019
DR   PRIDE; PXD023662
DR   Progenetix; CVCL_1047
DR   Wikidata; Q54585241
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=6334305;
RX   PubMed=8108117;
RX   PubMed=16408098;
RX   PubMed=16809887;
RX   PubMed=20164919;
RX   PubMed=26727417;
RX   PubMed=35354797;
CC   Doubling time: 3 days (PubMed=6334305); ~80 hours (DSMZ=ACC-39).
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): DSMZ
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D18S51: 12,13
ST   D19S433: 15,16
ST   D21S11: 28,29
ST   D2S1338: 16,17
ST   D3S1358: 16,18
ST   D5S818: 11,13
ST   D7S820: 9,11
ST   D8S1179: 11,13
ST   FGA: 19,20
ST   Penta D: 10,13
ST   Penta E: 9,11
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 16,17
DI   NCIt; C9140; Childhood B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 26
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
//
RX   PubMed=6334305; DOI=10.1073/pnas.81.22.7166;
RA   Pegoraro L., Palumbo A., Erikson J., Falda M., Giovanazzo B.,
RA   Emanuel B.S., Rovera G., Nowell P.C., Croce C.M.;
RT   "A 14;18 and an 8;14 chromosome translocation in a cell line derived
RT   from an acute B-cell leukemia.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:7166-7170(1984).
//
RX   PubMed=8108117;
RA   Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.;
RT   "Ongoing mutations in the N-terminal domain of c-Myc affect
RT   transactivation in Burkitt's lymphoma cell lines.";
RL   Oncogene 9:759-763(1994).
//
RX   PubMed=16408098; DOI=10.1038/sj.leu.2404081;
RA   Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.;
RT   "JAK2 V617F tyrosine kinase mutation in cell lines derived from
RT   myeloproliferative disorders.";
RL   Leukemia 20:471-476(2006).
//
RX   PubMed=16809887; DOI=10.1159/000092345;
RA   Takenokuchi M., Saigo K., Nakamachi Y., Kawano S., Hashimoto M.,
RA   Fujioka T., Koizumi T., Tatsumi E., Kumagai S.;
RT   "Troglitazone inhibits cell growth and induces apoptosis of B-cell
RT   acute lymphoblastic leukemia cells with t(14;18).";
RL   Acta Haematol. 116:30-40(2006).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=26727417; DOI=10.3109/10428194.2015.1108414;
RA   Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for double-hit
RT   B-cell lymphomas.";
RL   Leuk. Lymphoma 57:1015-1020(2016).
//
RX   PubMed=35354797; DOI=10.1038/s41467-022-29224-5;
RA   Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T.,
RA   Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E.,
RA   Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I.,
RA   Lehtio J., Vesterlund M., Jafari R.;
RT   "Integrative multi-omics and drug response profiling of childhood
RT   acute lymphoblastic leukemia cell lines.";
RL   Nat. Commun. 13:1691.1-1691.19(2022).
//