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Cellosaurus Panc1-bC2GnT-M (CVCL_0Q69)

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Cell line name Panc1-bC2GnT-M
Accession CVCL_0Q69
Resource Identification Initiative To cite this cell line use: Panc1-bC2GnT-M (RRID:CVCL_0Q69)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7508; MUC1.
Genetic integration: Method=Transfection/transduction; Gene=VGNC; VGNC:56968; Bovine GCNT1.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0Q68 (Panc1-MUC1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=10455130; DOI=10.1074/jbc.274.35.24641
Paul V. Beum, Jaswant Singh, Michael Burdick, Michael Anthony Hollingsworth, Pi-Wan Cheng;
Expression of core 2 beta-1,6-N-acetylglucosaminyltransferase in a human pancreatic cancer cell line results in altered expression of MUC1 tumor-associated epitopes.
J. Biol. Chem. 274:24641-24648(1999)

PubMed=22525330; DOI=10.1016/j.biocel.2012.04.004; PMCID=PMC4011501
Armen Petrosyan, Mohamed F. Ali, Shailendra Kumar Verma, Helen Cheng, Pi-Wan Cheng;
Non-muscle myosin IIA transports a Golgi glycosyltransferase to the endoplasmic reticulum by binding to its cytoplasmic tail.
Int. J. Biochem. Cell Biol. 44:1153-1165(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0Q69
Anatomy/cell type resources BTO; BTO_0005502
Encyclopedic resources Wikidata; Q54937556
Entry history
Entry creation08-Jul-2015
Last entry update19-Dec-2024
Version number15