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Cellosaurus L6-GLUT4myc (CVCL_0P25)

[Text version]
Cell line name L6-GLUT4myc
Synonyms L6-GLUT-4myc; L6 GLUT4myc
Accession CVCL_0P25
Resource Identification Initiative To cite this cell line use: L6-GLUT4myc (RRID:CVCL_0P25)
Comments Characteristics: Stably expresses Slc2a4/Glut4 containing a 14 amino-acid epitope of human MYC within its first exofacial loop. This construct allows the study of Slc2a4 translocation (PubMed=9607310; PubMed=10484371).
Genetic integration: Method=Transfection; Gene=RGD; 2711; Slc2a4 (Note=With a Myc tag in the 1st ectodomain).
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Thigh, skeletal muscle; UBERON=UBERON_0004252.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Hierarchy Parent: CVCL_0385 (L6)
Sex of cell Male
Age at sampling 1D
Category Transformed cell line
Publications

PubMed=9607310; DOI=10.1016/s0014-5793(98)00423-2
Wang Q.-H., Khayat Z., Kishi K., Ebina Y., Klip A.
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay.
FEBS Lett. 427:193-197(1998)

PubMed=10484371; DOI=10.1152/ajpendo.1999.277.3.E572
Ueyama A., Yaworsky K.L., Wang Q.-H., Ebina Y., Klip A.
GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity.
Am. J. Physiol. 277:E572-E578(1999)

PubMed=29218526; DOI=10.1007/978-1-4939-7507-5_14
Jaldin-Fincati J.R., Bilan P.J., Klip A.
GLUT4 translocation in single muscle cells in culture: epitope detection by immunofluorescence.
Methods Mol. Biol. 1713:175-192(2018)

Cross-references
Cell line collections (Providers) ABM; T0772
Kerafast; ESK202-FP
Encyclopedic resources Wikidata; Q54901054
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number15