ID   L6-GLUT4myc
AC   CVCL_0P25
SY   L6-GLUT-4myc; L6 GLUT4myc
DR   ABM; T0772
DR   Kerafast; ESK202-FP
DR   Wikidata; Q54901054
RX   PubMed=9607310;
RX   PubMed=10484371;
RX   PubMed=29218526;
CC   Characteristics: Stably expresses Slc2a4/Glut4 containing a 14 amino-acid epitope of human MYC within its first exofacial loop. This construct allows the study of Slc2a4 translocation (PubMed=9607310; PubMed=10484371).
CC   Genetic integration: Method=Transfection; Gene=RGD; 2711; Slc2a4 (Note=With a Myc tag in the 1st ectodomain).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Derived from site: In situ; Thigh, skeletal muscle; UBERON=UBERON_0004252.
CC   Cell type: Myoblast; CL=CL_0000056.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0385 ! L6
SX   Male
AG   1D
CA   Transformed cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 15
//
RX   PubMed=9607310; DOI=10.1016/s0014-5793(98)00423-2;
RA   Wang Q.-H., Khayat Z., Kishi K., Ebina Y., Klip A.;
RT   "GLUT4 translocation by insulin in intact muscle cells: detection by a
RT   fast and quantitative assay.";
RL   FEBS Lett. 427:193-197(1998).
//
RX   PubMed=10484371; DOI=10.1152/ajpendo.1999.277.3.E572;
RA   Ueyama A., Yaworsky K.L., Wang Q.-H., Ebina Y., Klip A.;
RT   "GLUT-4myc ectopic expression in L6 myoblasts generates a
RT   GLUT-4-specific pool conferring insulin sensitivity.";
RL   Am. J. Physiol. 277:E572-E578(1999).
//
RX   PubMed=29218526; DOI=10.1007/978-1-4939-7507-5_14;
RA   Jaldin-Fincati J.R., Bilan P.J., Klip A.;
RT   "GLUT4 translocation in single muscle cells in culture: epitope
RT   detection by immunofluorescence.";
RL   Methods Mol. Biol. 1713:175-192(2018).
//