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Cellosaurus AG06300 (CVCL_0J91)

[Text version]
Cell line name AG06300
Synonyms AG06300A
Accession CVCL_0J91
Resource Identification Initiative To cite this cell line use: AG06300 (RRID:CVCL_0J91)
Comments Population: Caucasian.
Senescence: Senesces at 35-40 PDL (Coriell=AG06300).
Karyotypic information: 47,XY,t(7;11)(11qter->11q23::7p22->7qter;11pter->11q23::7p22->7pter) [88%]; 46,XY[20].arr(1-22)x2,(X,Y)x1 [12%] (Coriell=AG06300).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Caution: Is stated not be from a Werner syndrome patient by PubMed=26984941.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_EQ39 (iWS300)
Sex of cell Male
Age at sampling 37Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587
Hoi-Hung Cheung, Xiao-Zhuo Liu, Lucile Canterel-Thouennon, Lu Li, Catherine Edmonson, Owen M. Rennert;
Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.
Stem Cell Reports 2:534-546(2014)

PubMed=26984941; DOI=10.1093/hmg/ddw079; PMCID=PMC5062591
Wei-Liang Tang, Ana I. Robles, Richard P. Beyer, Lucas T. Graybuck, Giang Huong Nguyen, Junko Oshima, Nancy Maizels, Curtis Craig Harris, Raymond J. Monnat Jr.;
The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.
Hum. Mol. Genet. 25:2060-2069(2016)

Cross-references
Cell line collections (Providers) Coriell; AG06300
Cell line databases/resources CLO; CLO_0035512
Encyclopedic resources Wikidata; Q54740303
Gene expression databases GEO; GSM1184270
GEO; GSM1184271
GEO; GSM1535459
GEO; GSM1535469
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number13