ID   AG06300
AC   CVCL_0J91
SY   AG06300A
DR   CLO; CLO_0035512
DR   Coriell; AG06300
DR   GEO; GSM1184270
DR   GEO; GSM1184271
DR   GEO; GSM1535459
DR   GEO; GSM1535469
DR   Wikidata; Q54740303
RX   CelloPub=CLPUB00597;
RX   PubMed=24749076;
RX   PubMed=26984941;
CC   Population: Caucasian.
CC   Senescence: Senesces at 35-40 PDL (Coriell=AG06300).
CC   Karyotypic information: 47,XY,t(7;11)(11qter->11q23::7p22->7qter;11pter->11q23::7p22->7pter) [88%]; 46,XY[20].arr(1-22)x2,(X,Y)x1 [12%] (Coriell=AG06300).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Caution: Is stated not be from a Werner syndrome patient by PubMed=26984941.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3447; Werner syndrome
DI   ORDO; Orphanet_902; Werner syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   37Y
CA   Finite cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 13
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994).
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RX   PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587;
RA   Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C.,
RA   Rennert O.M.;
RT   "Telomerase protects Werner syndrome lineage-specific stem cells from
RT   premature aging.";
RL   Stem Cell Reports 2:534-546(2014).
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RX   PubMed=26984941; DOI=10.1093/hmg/ddw079; PMCID=PMC5062591;
RA   Tang W.-L., Robles A.I., Beyer R.P., Graybuck L.T., Nguyen G.H.,
RA   Oshima J., Maizels N., Harris C.C., Monnat R.J. Jr.;
RT   "The Werner syndrome RECQ helicase targets G4 DNA in human cells to
RT   modulate transcription.";
RL   Hum. Mol. Genet. 25:2060-2069(2016).
//