ID   AG06300
AC   CVCL_0J91
SY   AG06300A
DR   CLO; CLO_0035512
DR   Coriell; AG06300
DR   GEO; GSM1184270
DR   GEO; GSM1184271
DR   GEO; GSM1535459
DR   GEO; GSM1535469
DR   Wikidata; Q54740303
RX   CelloPub=CLPUB00597;
RX   PubMed=24749076;
RX   PubMed=26984941;
CC   Population: Caucasian.
CC   Senescence: Senesces at 35-40 PDL (Coriell=AG06300).
CC   Karyotypic information: 47,XY,t(7;11)(11qter->11q23::7p22->7qter;11pter->11q23::7p22->7pter) [88%]; 46,XY[20].arr(1-22)x2,(X,Y)x1 [12%] (Coriell=AG06300).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Caution: Is stated not be from a Werner syndrome patient by PubMed=26984941.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3447; Werner syndrome
DI   ORDO; Orphanet_902; Werner syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   37Y
CA   Finite cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 13
CH   CVCL_EQ39 ! iWS300
//
RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994).
//
RX   PubMed=26984941; DOI=10.1093/hmg/ddw079; PMCID=PMC5062591;
RA   Tang, Wei-Liang
RA   Robles, Ana I.
RA   Beyer, Richard P.
RA   Graybuck, Lucas T.
RA   Nguyen, Giang Huong
RA   Oshima, Junko
RA   Maizels, Nancy
RA   Harris, Curtis Craig
RA   Monnat, Raymond J. Jr.
RT   "The Werner syndrome RECQ helicase targets G4 DNA in human cells to
RT   modulate transcription.";
RL   Hum. Mol. Genet. 25:2060-2069(2016).
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RX   PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587;
RA   Cheung, Hoi-Hung
RA   Liu, Xiao-Zhuo
RA   Canterel-Thouennon, Lucile
RA   Li, Lu
RA   Edmonson, Catherine
RA   Rennert, Owen Murray
RT   "Telomerase protects Werner syndrome lineage-specific stem cells from
RT   premature aging.";
RL   Stem Cell Reports 2:534-546(2014).
//