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Cellosaurus MP-CCS-SY (CVCL_0J33)

[Text version]
Cell line name MP-CCS-SY
Synonyms Miyazaki Pediatrics-Clear cell Sarcoma-SY
Accession CVCL_0J33
Resource Identification Initiative To cite this cell line use: MP-CCS-SY (RRID:CVCL_0J33)
Comments Population: Japanese.
Doubling time: 36 hours (PubMed=12072203).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=12072203; PubMed=28745431).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17-18Y
Category Cancer cell line
STR profile Source(s): PubMed=36959380

Markers:
AmelogeninX
CSF1PO9,12
D3S135817
D5S8189,12
D7S8208,13
D8S117913,14
D13S31711,12
D16S5399,11
D18S5114,25
D21S1130,32.2
FGA20,22
Penta D9,11
Penta E11,12
TH017,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=12072203; DOI=10.1016/S0165-4608(01)00641-0
Hiroshi Moritake, Tohru Sugimoto, Yujiro Asada, Mitsuaki A. Yoshida, Yoshihiko Maehara, Alan L. Epstein, Hiroshi Kuroda;
Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene.
Cancer Genet. Cytogenet. 135:48-56(2002)

PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837
Takaaki Nakai, Yoshinori Imura, Hironari Tamiya, Shutaro Yamada, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui ...Show all 16 authors... , Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka; Show fewer authors
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
Cancer Med. 6:2121-2130(2017)

CLPUB00599
Tohru Sugimoto, Hiroshi Kuroda, Yasumichi Kuwahara, Yoshiki Katsumi, Akiko Misawa, Hiroshi Moritake, Hajime Hosoi;
Cellular and molecular characteristics of established childhood soft-tissue sarcoma cell lines.
J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Samuel V. Rasmussen, Agnieszka Wozniak, Melvin Lathara, Joshua M. Goldenberg, Benjamin Michael Samudio, Lissett Ramirez Bickford, Kiyo Nagamori, Hollis Wright, Andrew D. Woods, Shefali Chauhan, Che-Jui Lee ...Show all 30 authors... , Erin R. Rudzinski, Michael K. Swift, Tadashi Kondo, David Erich Fisher, Evgeny N. Imyanitov, Isidro Machado, Antonio Llombart-Bosch, Irene L. Andrulis, Nalan Gokgoz, Jay Steven Wunder, Hiroshi Moritake, Takuro Nakamura, Ganapati Srinivasa, Khin Thway, Robin L. Jones, Paul H. Huang, Noah E. Berlow, Patrick Schoffski, Charles Keller; Show fewer authors
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)

Cross-references
Encyclopedic resources Wikidata; Q28726672
Sequence databases EGA; EGAD00001008611
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number14