ID   MP-CCS-SY
AC   CVCL_0J33
SY   Miyazaki Pediatrics-Clear cell Sarcoma-SY
DR   EGA; EGAD00001008611
DR   Wikidata; Q28726672
RX   CelloPub=CLPUB00599;
RX   PubMed=12072203;
RX   PubMed=28745431;
RX   PubMed=36959380;
CC   Population: Japanese.
CC   Doubling time: 36 hours (PubMed=12072203).
CC   Sequence variation: Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=12072203; PubMed=28745431).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
ST   Source(s): PubMed=36959380
ST   Amelogenin: X
ST   CSF1PO: 9,12
ST   D13S317: 11,12
ST   D16S539: 9,11
ST   D18S51: 14,25
ST   D21S11: 30,32.2
ST   D3S1358: 17
ST   D5S818: 9,12
ST   D7S820: 8,13
ST   D8S1179: 13,14
ST   FGA: 20,22
ST   Penta D: 9,11
ST   Penta E: 11,12
ST   TH01: 7,9.3
ST   TPOX: 8,11
ST   vWA: 14
DI   NCIt; C3745; Clear cell sarcoma of soft tissue
DI   ORDO; Orphanet_3394; Soft tissue sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   17-18Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 10-04-25; Version: 14
//
RX   PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623;
RA   Rasmussen, Samuel V.
RA   Wozniak, Agnieszka
RA   Lathara, Melvin
RA   Goldenberg, Joshua M.
RA   Samudio, Benjamin Michael
RA   Bickford, Lissett Ramirez
RA   Nagamori, Kiyo
RA   Wright, Hollis
RA   Woods, Andrew D.
RA   Chauhan, Shefali
RA   Lee, Che-Jui
RA   Rudzinski, Erin R.
RA   Swift, Michael K.
RA   Kondo, Tadashi
RA   Fisher, David Erich
RA   Imyanitov, Evgeny N.
RA   Machado, Isidro
RA   Llombart-Bosch, Antonio
RA   Andrulis, Irene L.
RA   Gokgoz, Nalan
RA   Wunder, Jay Steven
RA   Moritake, Hiroshi
RA   Nakamura, Takuro
RA   Srinivasa, Ganapati
RA   Thway, Khin
RA   Jones, Robin L.
RA   Huang, Paul H.
RA   Berlow, Noah E.
RA   Schoffski, Patrick
RA   Keller, Charles
RT   "Functional genomics of human clear cell sarcoma: genomic,
RT   transcriptomic and chemical biology landscape for clear cell sarcoma.";
RL   Br. J. Cancer 128:1941-1954(2023).
//
RX   PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837;
RA   Nakai, Takaaki
RA   Imura, Yoshinori
RA   Tamiya, Hironari
RA   Yamada, Shutaro
RA   Nakai, Sho
RA   Yasuda, Naohiro
RA   Kaneko, Keiko
RA   Outani, Hidetatsu
RA   Takenaka, Satoshi
RA   Hamada, Kenichiro
RA   Myoui, Akira
RA   Araki, Nobuhito
RA   Ueda, Takafumi
RA   Itoh, Kazuyuki
RA   Yoshikawa, Hideki
RA   Naka, Norifumi
RT   "Trabectedin is a promising antitumor agent potentially inducing
RT   melanocytic differentiation for clear cell sarcoma.";
RL   Cancer Med. 6:2121-2130(2017).
//
RX   PubMed=12072203; DOI=10.1016/S0165-4608(01)00641-0;
RA   Moritake, Hiroshi
RA   Sugimoto, Tohru
RA   Asada, Yujiro
RA   Yoshida, Mitsuaki A.
RA   Maehara, Yoshihiko
RA   Epstein, Alan L.
RA   Kuroda, Hiroshi
RT   "Newly established clear cell sarcoma (malignant melanoma of soft
RT   parts) cell line expressing melanoma-associated Melan-A antigen and
RT   overexpressing C-MYC oncogene.";
RL   Cancer Genet. Cytogenet. 135:48-56(2002).
//
RX   CelloPub=CLPUB00599;
RA   Sugimoto, Tohru
RA   Kuroda, Hiroshi
RA   Kuwahara, Yasumichi
RA   Katsumi, Yoshiki
RA   Misawa, Akiko
RA   Moritake, Hiroshi
RA   Hosoi, Hajime
RT   "Cellular and molecular characteristics of established childhood
RT   soft-tissue sarcoma cell lines.";
RL   J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019).
//