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Cellosaurus 17CM98 (CVCL_0C82)

[Text version]
Cell line name 17CM98
Accession CVCL_0C82
Resource Identification Initiative To cite this cell line use: 17CM98 (RRID:CVCL_0C82)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 22 hours (PubMed=27257868).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; VGNC; 42422; KIT; Simple; p.Val558_Glu560del (c.1673_1681delTTGTTGAGG); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine oral melanoma (NCIt: C185639)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Markers:
Dog FHC2010231
Dog FHC2054156
Dog FHC2079271
Dog PEZ1127
Dog PEZ12270,274
Dog PEZ20176
Dog PEZ3121,131
Dog PEZ5107
Dog PEZ6176
Dog PEZ8236,240

Run an STR similarity search on this cell line
Publications

PubMed=15965647; DOI=10.1007/s00262-005-0025-6
Alexander A.N., Huelsmeyer M.K., Mitzey A., Dubielzig R.R., Kurzman I.D., MacEwen E.G., Vail D.M.
Development of an allogeneic whole-cell tumor vaccine expressing xenogeneic gp100 and its implementation in a phase II clinical trial in canine patients with malignant melanoma.
Cancer Immunol. Immunother. 55:433-442(2006)

PubMed=22901430; DOI=10.1016/j.jcpa.2012.07.001
Chon E., Thompson V., Schmid S., Stein T.J.
Activation of the canonical Wnt/beta-catenin signalling pathway is rare in canine malignant melanoma tissue and cell lines.
J. Comp. Pathol. 148:178-187(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cross-references
Encyclopedic resources Wikidata; Q54582441
Gene expression databases GEO; GSM1974774
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number12