Cellosaurus cell line INV-3 (CVCL

Cellosaurus INV-3 (CVCL_0C65)

Cross-references
Cell line name	INV-3
Synonyms	inv-3
Accession	CVCL_0C65
Resource Identification Initiative	To cite this cell line use: INV-3 (RRID:CVCL_0C65)
Sequence variations	Mutation; HGNC; 9644; PTPN11; Simple; p.Asp61Val (c.182A>T); ClinVar=VCV000040496; Zygosity=Unspecified (PubMed=16518851).
Disease	Acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2) GATA2, MECOM (NCIt: C82426) Acute myeloid leukemia with inv3(q21;q26.2) or t(3;3)(q21;q26.2) (ORDO: Orphanet_402020)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=16518851; DOI=10.1002/gcc.20322 Chen Y.-Y., Takita J., Hiwatari M., Igarashi T., Hanada R., Kikuchi A., Hongo T., Taki T., Ogasawara M., Shimada A., Hayashi Y. Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. Genes Chromosomes Cancer 45:583-591(2006) PubMed=23955599; DOI=10.1038/ng.2731 Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K.-i., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.-K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S. Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nat. Genet. 45:1232-1237(2013)
Cell line databases/resources	cancercelllines; CVCL_0C65
Encyclopedic resources	Wikidata; Q54897827
Polymorphism and mutation databases	Cosmic; 1037662 Cosmic; 2089661
Entry history
Entry creation	10-Apr-2015
Last entry update	05-Oct-2023
Version number	7