ID   INV-3
AC   CVCL_0C65
SY   inv-3
DR   cancercelllines; CVCL_0C65
DR   Cosmic; 1037662
DR   Cosmic; 2089661
DR   Wikidata; Q54897827
RX   PubMed=16518851;
RX   PubMed=23955599;
CC   Sequence variation: Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Asp61Val (c.182A>T); ClinVar=VCV000040496; Zygosity=Unspecified (PubMed=16518851).
DI   NCIt; C82426; Acute myeloid leukemia with inv(3) (q21.3;q26.2) or t(3;3) (q21.3;q26.2) GATA2, MECOM
DI   ORDO; Orphanet_402020; Acute myeloid leukemia with inv3(q21;q26.2) or t(3;3)(q21;q26.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 8
//
RX   PubMed=23955599; DOI=10.1038/ng.2731;
RA   Kon, Ayana
RA   Shih, Lee-Yung
RA   Minamino, Masashi
RA   Sanada, Masashi
RA   Shiraishi, Yuichi
RA   Nagata, Yasunobu
RA   Yoshida, Ken-ichi
RA   Okuno, Yusuke
RA   Bando, Masashige
RA   Nakato, Ryuichiro
RA   Ishikawa, Shumpei
RA   Sato-Otsubo, Aiko
RA   Nagae, Genta
RA   Nishimoto, Aiko
RA   Haferlach, Claudia
RA   Nowak, Daniel
RA   Sato, Yusuke
RA   Alpermann, Tamara
RA   Nagasaki, Masao
RA   Shimamura, Teppei
RA   Tanaka, Hiroko
RA   Chiba, Kenichi
RA   Yamamoto, Ryo
RA   Yamaguchi, Tomoyuki
RA   Otsu, Makoto
RA   Obara, Naoshi
RA   Sakata-Yanagimoto, Mamiko
RA   Nakamaki, Tsuyoshi
RA   Ishiyama, Ken
RA   Nolte, Florian
RA   Hofmann, Wolf-Karsten
RA   Miyawaki, Shuichi
RA   Chiba, Shigeru
RA   Mori, Hiraku
RA   Nakauchi, Hiromitsu
RA   Koeffler, Harold Phillip
RA   Aburatani, Hiroyuki
RA   Haferlach, Torsten
RA   Shirahige, Katsuhiko
RA   Miyano, Satoru
RA   Ogawa, Seishi
RT   "Recurrent mutations in multiple components of the cohesin complex in
RT   myeloid neoplasms.";
RL   Nat. Genet. 45:1232-1237(2013).
//
RX   PubMed=16518851; DOI=10.1002/gcc.20322;
RA   Chen, Yu-Yan
RA   Takita, Junko
RA   Hiwatari, Mitsuteru
RA   Igarashi, Takashi
RA   Hanada, Ryoji
RA   Kikuchi, Akira
RA   Hongo, Teruaki
RA   Taki, Tomohiko
RA   Ogasawara, Mizuho
RA   Shimada, Akira
RA   Hayashi, Yasuhide
RT   "Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and
RT   pediatric hematological malignancies.";
RL   Genes Chromosomes Cancer 45:583-591(2006).
//