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Cellosaurus HCC-1.2 (CVCL_0C53)

[Text version]
Cell line name HCC-1.2
Synonyms HCC.1.2; HCC1.2; 1.2; 3P; 3p
Accession CVCL_0C53
Resource Identification Initiative To cite this cell line use: HCC-1.2 (RRID:CVCL_0C53)
Comments Miscellaneous: Direct author submission of STR profile from Rohr-Udilova N.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatitis C infection (NCIt: C3098)
Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0C42 ! BLC-1
CVCL_0C52 ! HCC-1.1
CVCL_0C47 ! MF-1 [Human]
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO10,12
D3S135815,16
D5S81810,13
D7S8209,10
D8S117911,13
D13S31712
D16S5399
D18S5114,16
D21S1128,29
FGA20
Penta D12,13
Penta E10,12
TH017,9.3
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages https://lccl.zucmanlab.com/hcc/cellLines/HCC.1.2
Publications

PubMed=18594539; DOI=10.1038/sj.bjc.6604440
Sagmeister S., Eisenbauer M., Pirker C., Mohr T., Holzmann K., Zwickl H., Bichler C., Kandioler D., Wrba F., Mikulits W., Gerner C., Shehata M., Majdic O., Streubel B., Berger W., Micksche M., Zatloukal K., Schulte-Hermann R., Grasl-Kraupp B.
New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis.
Br. J. Cancer 99:151-159(2008)

PubMed=21364009; DOI=10.1158/1535-7163.MCT-10-0917
van Zijl F., Mall S., Machat G., Pirker C., Zeillinger R., Weinhaeusel A., Bilban M., Berger W., Mikulits W.
A human model of epithelial to mesenchymal transition to monitor drug efficacy in hepatocellular carcinoma progression.
Mol. Cancer Ther. 10:850-860(2011)

PubMed=23887712; DOI=10.1038/ncomms3218
Nault J.-C., Mallet M., Pilati C., Calderaro J., Bioulac-Sage P., Laurent C., Laurent A., Cherqui D., Balabaud C., Zucman-Rossi J.
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
Nat. Commun. 4:2218.1-2218.7(2013)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4295407
ChEMBL-Targets; CHEMBL4296419
PubChem_Cell_line; CVCL_0C53
Encyclopedic resources Wikidata; Q54881505
Polymorphism and mutation databases Cosmic; 1628382
Cosmic; 2162520
Cosmic; 2162521
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number10