ID   HCC-1.2
AC   CVCL_0C53
SY   HCC.1.2; HCC1.2; 1.2; 3P; 3p
DR   ChEMBL-Cells; CHEMBL4295407
DR   ChEMBL-Targets; CHEMBL4296419
DR   Cosmic; 1628382
DR   Cosmic; 2162520
DR   Cosmic; 2162521
DR   PubChem_Cell_line; CVCL_0C53
DR   Wikidata; Q54881505
RX   PubMed=18594539;
RX   PubMed=21364009;
RX   PubMed=23887712;
WW   https://lccl.zucmanlab.com/hcc/cellLines/HCC.1.2
CC   Miscellaneous: Direct author submission of STR profile from Rohr-Udilova N.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 9
ST   D18S51: 14,16
ST   D21S11: 28,29
ST   D3S1358: 15,16
ST   D5S818: 10,13
ST   D7S820: 9,10
ST   D8S1179: 11,13
ST   FGA: 20
ST   Penta D: 12,13
ST   Penta E: 10,12
ST   TH01: 7,9.3
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C3098; Hepatitis C infection
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_0C42 ! BLC-1
OI   CVCL_0C52 ! HCC-1.1
OI   CVCL_0C47 ! MF-1 [Human]
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 29-06-23; Version: 10
//
RX   PubMed=18594539; DOI=10.1038/sj.bjc.6604440;
RA   Sagmeister S., Eisenbauer M., Pirker C., Mohr T., Holzmann K.,
RA   Zwickl H., Bichler C., Kandioler D., Wrba F., Mikulits W., Gerner C.,
RA   Shehata M., Majdic O., Streubel B., Berger W., Micksche M.,
RA   Zatloukal K., Schulte-Hermann R., Grasl-Kraupp B.;
RT   "New cellular tools reveal complex epithelial-mesenchymal interactions
RT   in hepatocarcinogenesis.";
RL   Br. J. Cancer 99:151-159(2008).
//
RX   PubMed=21364009; DOI=10.1158/1535-7163.MCT-10-0917;
RA   van Zijl F., Mall S., Machat G., Pirker C., Zeillinger R.,
RA   Weinhaeusel A., Bilban M., Berger W., Mikulits W.;
RT   "A human model of epithelial to mesenchymal transition to monitor drug
RT   efficacy in hepatocellular carcinoma progression.";
RL   Mol. Cancer Ther. 10:850-860(2011).
//
RX   PubMed=23887712; DOI=10.1038/ncomms3218;
RA   Nault J.-C., Mallet M., Pilati C., Calderaro J., Bioulac-Sage P.,
RA   Laurent C., Laurent A., Cherqui D., Balabaud C., Zucman-Rossi J.;
RT   "High frequency of telomerase reverse-transcriptase promoter somatic
RT   mutations in hepatocellular carcinoma and preneoplastic lesions.";
RL   Nat. Commun. 4:2218.1-2218.7(2013).
//