| Cell line name |
Capan1M9 |
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| Accession |
CVCL_0A59 |
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| Resource Identification Initiative |
To cite this cell line use: Capan1M9 (RRID:CVCL_0A59) |
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| Comments |
Population: Caucasian.
Characteristics: Highly migratory cell subclone of Capan-1.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
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| Sequence variations |
- Mutation; HGNC; 1101; BRCA2; Simple; p.Ser1982Argfs*22 (c.5946delT) (6174delT); ClinVar=VCV000009325; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; 4039; FZD10; Simple; p.Asn54Lys (c.162C>A); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 23671; GLT6D1; Simple; p.Trp198Ter (c.593G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 4593; GRM1; Simple; p.Tyr486Ter (c.1458C>A); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 6844; MAP2K4; Simple; p.Glu221Ter (c.661G>T); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 6770; SMAD4; Simple; p.Ser343Ter (c.1028C>G); ClinVar=VCV000822036; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 25082; SMAP2; Simple; p.Ser255Ter (c.764C>G); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Ala159Val (c.476C>T); ClinVar=VCV000458545; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Pancreatic ductal adenocarcinoma (NCIt: C9120) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0237 (Capan-1) |
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| Sex of cell |
Male |
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| Age at sampling |
40Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=22109279; DOI=10.1007/s13577-011-0037-9
Ding Q., Yoshimitsu M., Kuwahata T., Maeda K., Hayashi T., Obara T., Miyazaki Y., Matsubara S., Natsugoe S., Takao S.
Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer.
Hum. Cell 25:1-8(2012) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_0A59
|
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| Encyclopedic resources |
Wikidata; Q54808592
|
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| Entry history |
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| Entry creation | 10-Apr-2015 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 15 |
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