ID   Capan1M9
AC   CVCL_0A59
DR   cancercelllines; CVCL_0A59
DR   Wikidata; Q54808592
RX   PubMed=22109279;
CC   Population: Caucasian.
CC   Characteristics: Highly migratory cell subclone of Capan-1.
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser1982Argfs*22 (c.5946delT) (6174delT); ClinVar=VCV000009325; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4039; FZD10; Simple; p.Asn54Lys (c.162C>A); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:23671; GLT6D1; Simple; p.Trp198Ter (c.593G>A); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4593; GRM1; Simple; p.Tyr486Ter (c.1458C>A); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6844; MAP2K4; Simple; p.Glu221Ter (c.661G>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Ser343Ter (c.1028C>G); ClinVar=VCV000822036; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:25082; SMAP2; Simple; p.Ser255Ter (c.764C>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala159Val (c.476C>T); ClinVar=VCV000458545; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0237 ! Capan-1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 16
//
RX   PubMed=22109279; DOI=10.1007/s13577-011-0037-9;
RA   Ding, Qiang
RA   Yoshimitsu, Makoto
RA   Kuwahata, Taisaku
RA   Maeda, Koki
RA   Hayashi, Tomomi
RA   Obara, Toru
RA   Miyazaki, Yumi
RA   Matsubara, Shyuichiro
RA   Natsugoe, Shoji
RA   Takao, Sonshin
RT   "Establishment of a highly migratory subclone reveals that CD133
RT   contributes to migration and invasion through epithelial-mesenchymal
RT   transition in pancreatic cancer.";
RL   Hum. Cell 25:1-8(2012).
//