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Cellosaurus Ku812F (CVCL_0616)

[Text version]
Cell line name Ku812F
Synonyms KU812F; KU-812-F; KU-812F; KU 812F; KU812-F
Accession CVCL_0616
Resource Identification Initiative To cite this cell line use: Ku812F (RRID:CVCL_0616)
Comments Population: Japanese.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Basophil progenitor cell; CL=CL_0000613.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys132Arg (c.395A>G); ClinVar=VCV000376625; Zygosity=Homozygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0379 (Ku812)
Sex of cell Male
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): ATCC; ECACC; Genomics_Center_BCF_Technion; JCRB; PubMed=11416159; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO12,13
D1S165616,18
D2S44111
D2S133818
D3S135815
D5S81810
D7S82012
D8S117911,15
D10S124814
D12S39117
D13S3178
D16S5399
D18S5113
D19S43313,14
D21S1130,31.2
D22S104511
DYS39110
FGA22,24
Penta D12
Penta E5,19
TH019
TPOX12
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=3304457; DOI=10.1182/blood.V70.3.612.612
Fukuda T., Kishi K., Ohnishi Y., Shibata A.
Bipotential cell differentiation of KU-812: evidence of a hybrid cell line that differentiates into basophils and macrophage-like cells.
Blood 70:612-619(1987)

PubMed=2540861; DOI=10.1182/blood.V73.7.2003.2003
Nakazawa M., Mitjavila-Garcia M.-T., Debili N., Casadevall N., Mayeux P., Rouyer-Fessard P., Dubart-Kupperschmitt A., Romeo P.-H., Beuzard Y., Kishi K., Breton-Gorius J., Vainchenker W.
KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation.
Blood 73:2003-2013(1989)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=11416159; DOI=10.1073/pnas.121616198
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

Cross-references
Cell line collections (Providers) ATCC; CRL-2101
ECACC; 90071804
JCRB; JCRB0104.2
RCB; RCB0497
RCB; RCB3053 - Discontinued
TKG; TKG 0304
Cell line databases/resources CLO; CLO_0007127
CLO; CLO_0050974
CLO; CLO_0051002
CLDB; cl3072
cancercelllines; CVCL_0616
LINCS_LDP; LCL-1108
Anatomy/cell type resources BTO; BTO:0003142
Biological sample resources BioSample; SAMN01821695
Encyclopedic resources Wikidata; Q54900696
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23