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Cellosaurus WGA (CVCL_0578)

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Cell line name WGA
Accession CVCL_0578
Resource Identification Initiative To cite this cell line use: WGA (RRID:CVCL_0578)
Comments Population: Caucasian.
Characteristics: Derived from the parent cell line by metabolic selection using the ability to grow on fructose as the selection system.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=15572372; DOI=10.1074/jbc.M412711200
Franck Rencurel, Alasdair Stenhouse, Simon A. Hawley, Thomas Friedberg, David Grahame Hardie, Calum Sutherland, Charles Roland Wolf;
AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.
J. Biol. Chem. 280:4367-4373(2005)

Cross-references
Cell line databases/resources MCCL; MCC:0000484
cancercelllines; CVCL_0578
Encyclopedic resources Wikidata; Q54993989
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18