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Cellosaurus SW1353 (CVCL_0543)

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Cell line name SW1353
Synonyms SW-1353; SW 1353
Accession CVCL_0543
Resource Identification Initiative To cite this cell line use: SW1353 (RRID:CVCL_0543)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: MD Anderson Cell Lines Project.
From: Scott and White Clinic; Temple; USA.
Population: Caucasian.
Karyotypic information: Hyperdiploid, 47,XX,+7 (ATCC=HTB-94).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; Subcellular; Secretome.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; Ribosome profiling; Ribo-Seq.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone, right humerus; UBERON=UBERON_0000976.
Sequence variations
HLA typing Source: PubMed=26589293
Class I
HLA-AA*24:02,29:02
HLA-BB*44:02,44:02
HLA-CC*02:02,16:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.24
Native American0
East Asian, North2.24
East Asian, South0
South Asian0
European, North66.16
European, South31.35
Disease Primary central chondrosarcoma (NCIt: C7155)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E3IP (HyCyte SW1353-Luc)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-94; CLS=300440; IZSLER=BS TCL 213; PubMed=19787792; Technion Genomics Center

Markers:
AmelogeninX
CSF1PO12
D1S165611,17.3
D2S44111,14
D2S133819,24
D3S135815,18
D5S81810,11
D7S8209,11
D8S117910,11
D10S124813,16
D12S39122,23
D13S31712,13
D16S53911,12
D18S5113,17
D19S43314
D21S1130,32.2
D22S104515,17
FGA22,23
Penta D10,11
Penta E12,14
SE3319,21
TH016,9
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=3518877; DOI=10.3109/07357908609038260
Jorgen Fogh;
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

DOI=10.1007/978-94-011-3550-4_4
Robert J. Hay;
Development, availability and characterization of ATCC human and animal cell lines.
(In book chapter) Animal cell culture and production of biologicals; Sasaki, Ryuzo & Ikura, Koji (eds.); pp.27-39; Springer; Dordrecht; Netherlands (1991)

PubMed=15950496; DOI=10.1016/j.joca.2005.04.004
Mathias Gebauer, Joachim Saas, Florian Sohler, Jochen Haag, Stephan Soder, Monika Pieper, Eckart Bartnik, Jochen Beninga, Ralf Zimmer, Thomas Aigner;
Comparison of the chondrosarcoma cell line SW1353 with primary human adult articular chondrocytes with regard to their gene expression profile and reactivity to IL-1beta.
Osteoarthritis Cartilage 13:697-708(2005)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22057234; DOI=10.1038/ng.1004; PMCID=PMC3427908
Twinkal Marfatia, Ronald van Eijk, Pio d'Adamo, Maayke A.J.H. van Ruler, Marieke Lydia Kuijjer, Jan Oosting, Anne-Marie Cleton-Jansen, Jolieke G. van Oosterwijk, Sofie L.J. Verbeke, Danielle Meijer, Tom van Wezel ...Show all 27 authors... , Karolin H. Nord, Luca Sangiorgi, Berkin Toker, Bernadette Liegl-Atzwanger, Mikel San-Julian, Raf Sciot, Nisha Limaye, Lars-Gunnar Kindblom, Soeren Daugaard, Catherine Godfraind, Laurence M. Boon, Miikka Vikkula, Kyle C. Kurek, Karoly Szuhai, Pim J. French, Judith V.M.G. Bovee; Show fewer authors
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Nat. Genet. 43:1256-1261(2011)

PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027
Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476
Beverly A. Teicher, Eric C. Polley, Mark W. Kunkel, David Evans, Thomas E. Silvers, Rene M. Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly ...Show all 14 authors... , Erik Harris, Anne Monks, Joel Morris; Show fewer authors
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Supriya Kumar Saha, John D. Gordan, Benjamin P. Kleinstiver, Phuong Vu, Mortada S. Najem, Jia-Chi Yeo, Lei Shi, Yasutaka Kato, Rebecca S. Levin, James T. Webber, Leah J. Damon ...Show all 28 authors... , Regina K. Egan, Patricia Greninger, Ultan McDermott, Mathew J. Garnett, Roger L. Jenkins, Kimberly M. Rieger-Christ, Travis B. Sullivan, Aram Francis Hezel, Andrew S. Liss, Yusuke Mizukami, Lipika Goyal, Cristina Rosa Ferrone, Andrew Xiu-Xuan Zhu, Jae Keith Joung, Kevan Michael Shokat, Cyril Henri Benes, Nabeel M. Bardeesy; Show fewer authors
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29853780; DOI=10.1155/2018/3082526; PMCID=PMC5964616
Abdulazeez Salawu, Kristin Wright, Afnan Al-Kathiri, Lynda Wyld, Malcolm Walter Ronald Reed, Karen Sisley;
Sister chromatid exchange and genomic instability in soft tissue sarcomas: potential implications for response to DNA-damaging treatments.
Sarcoma 2018:3082526.1-3082526.8(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich;
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103
Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31300557; DOI=10.1074/jbc.RA118.006865; PMCID=PMC6721953
Benjamin Thomas McDermott, Mandy J. Peffers, Brian McDonagh, Simon R. Tew;
Translational regulation contributes to the secretory response of chondrocytic cells following exposure to interleukin-1beta.
J. Biol. Chem. 294:13027-13039(2019)

Cross-references
Cell line collections (Providers) ATCC; HTB-94
BCRC; 60548
BCRJ; 0382
CLS; 300440
ICLC; HTL99008
IZSLER; BS TCL 213
NCBI_Iran; C571
Ubigene; YC-C105
Cell line databases/resources CLO; CLO_0009186
CLO; CLO_0009210
MCCL; MCC:0000443
CLDB; cl4957
cancercelllines; CVCL_0543
CCRID; 3101HUMTCHu128
Cell_Model_Passport; SIDM01766
DepMap; ACH-000418
IGRhCellID; SW1353
Lonza; 85
TOKU-E; 3213
Anatomy/cell type resources BTO; BTO_0002003
Biological sample resources BioSample; SAMN03472765
BioSample; SAMN10988195
Chemistry resources ChEMBL-Cells; CHEMBL3307462
ChEMBL-Targets; CHEMBL614944
PharmacoDB; SW1353_1525_2019
PubChem_Cell_line; CVCL_0543
Encyclopedic resources Wikidata; Q54971078
Experimental variables resources EFO; EFO_0002360
Gene expression databases ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-7466
FANTOM5_SSTAR; 10700-109G7
GEO; GSM887666
GEO; GSM888758
GEO; GSM1670499
GEO; GSM1676319
GEO; GSM1701652
Polymorphism and mutation databases Cosmic; 923378
Cosmic; 1602475
Cosmic; 1992321
IARC_TP53; 27036
LiGeA; CCLE_285
Progenetix; CVCL_0543
Proteomic databases PRIDE; PXD012985
PRIDE; PXD024953
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number41