ID   SW1353
AC   CVCL_0543
SY   SW-1353; SW 1353
DR   BTO; BTO:0002003
DR   CLO; CLO_0009186
DR   CLO; CLO_0009210
DR   EFO; EFO_0002360
DR   MCCL; MCC:0000443
DR   CLDB; cl4957
DR   ArrayExpress; E-MTAB-38
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-7466
DR   ATCC; HTB-94
DR   BCRC; 60548
DR   BCRJ; 0382
DR   BioSample; SAMN03472765
DR   BioSample; SAMN10988195
DR   cancercelllines; CVCL_0543
DR   CCRID; 3101HUMTCHu128
DR   Cell_Model_Passport; SIDM01766
DR   ChEMBL-Cells; CHEMBL3307462
DR   ChEMBL-Targets; CHEMBL614944
DR   CLS; 300440
DR   Cosmic; 923378
DR   Cosmic; 1602475
DR   Cosmic; 1992321
DR   DepMap; ACH-000418
DR   GEO; GSM887666
DR   GEO; GSM888758
DR   GEO; GSM1670499
DR   GEO; GSM1676319
DR   GEO; GSM1701652
DR   IARC_TP53; 27036
DR   ICLC; HTL99008
DR   IGRhCellID; SW1353
DR   IZSLER; BS TCL 213
DR   LiGeA; CCLE_285
DR   Lonza; 85
DR   NCBI_Iran; C571
DR   PharmacoDB; SW1353_1525_2019
DR   PRIDE; PXD012985
DR   PRIDE; PXD024953
DR   Progenetix; CVCL_0543
DR   PubChem_Cell_line; CVCL_0543
DR   TOKU-E; 3213
DR   Ubigene; YC-C105
DR   Wikidata; Q54971078
RX   DOI=10.1007/978-94-011-3550-4_4;
RX   PubMed=3518877;
RX   PubMed=15950496;
RX   PubMed=19787792;
RX   PubMed=20215515;
RX   PubMed=22057234;
RX   PubMed=22460905;
RX   PubMed=26351324;
RX   PubMed=26589293;
RX   PubMed=27231123;
RX   PubMed=28196595;
RX   PubMed=29853780;
RX   PubMed=30894373;
RX   PubMed=31068700;
WW   https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: MD Anderson Cell Lines Project.
CC   From: Scott and White Clinic; Temple; USA.
CC   Population: Caucasian.
CC   HLA typing: A*24:02,29:02; B*44:02,44:02; C*02:02,16:01 (PubMed=26589293).
CC   Karyotypic information: Hyperdiploid, 47,XX,+7 (ATCC=HTB-94).
CC   Sequence variation: Mutation; HGNC; 5383; IDH2; Simple; p.Arg172Ser (c.516G>C); ClinVar=VCV000375985; Zygosity=Heterozygous (PubMed=22057234; DepMap=ACH-000418).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val203Leu (c.607G>C); ClinVar=VCV000482235; Zygosity=Heterozygous (PubMed=19787792; DepMap=ACH-000418).
CC   Omics: Deep exome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: Ribosome profiling.
CC   Omics: Secretome proteome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0.24%; Native American=0%; East Asian, North=2.24%; East Asian, South=0%; South Asian=0%; European, North=66.16%; European, South=31.35% (PubMed=30894373).
CC   Derived from site: In situ; Bone, right humerus; UBERON=UBERON_0000976.
ST   Source(s): ATCC=HTB-94; CLS=300440; IZSLER=BS TCL 213; PubMed=19787792; Technion Genomics Center
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 13,16
ST   D12S391: 22,23
ST   D13S317: 12,13
ST   D16S539: 11,12
ST   D18S51: 13,17
ST   D19S433: 14
ST   D1S1656: 11,17.3
ST   D21S11: 30,32.2
ST   D22S1045: 15,17
ST   D2S1338: 19,24
ST   D2S441: 11,14
ST   D3S1358: 15,18
ST   D5S818: 10,11
ST   D7S820: 9,11
ST   D8S1179: 10,11
ST   FGA: 22,23
ST   Penta D: 10,11
ST   Penta E: 12,14
ST   SE33: 19,21
ST   TH01: 6,9
ST   TPOX: 8,11
ST   vWA: 16,17
DI   NCIt; C7155; Primary central chondrosarcoma
DI   ORDO; Orphanet_55880; Chondrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   72Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 39
//
RX   DOI=10.1007/978-94-011-3550-4_4;
RA   Hay R.J.;
RT   "Development, availability and characterization of ATCC human and
RT   animal cell lines.";
RL   (In book chapter) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.27-39; Springer; Dordrecht; Netherlands (1991).
//
RX   PubMed=3518877; DOI=10.3109/07357908609038260;
RA   Fogh J.;
RT   "Human tumor lines for cancer research.";
RL   Cancer Invest. 4:157-184(1986).
//
RX   PubMed=15950496; DOI=10.1016/j.joca.2005.04.004;
RA   Gebauer M., Saas J., Sohler F., Haag J., Soder S., Pieper M.,
RA   Bartnik E., Beninga J., Zimmer R., Aigner T.;
RT   "Comparison of the chondrosarcoma cell line SW1353 with primary human
RT   adult articular chondrocytes with regard to their gene expression
RT   profile and reactivity to IL-1beta.";
RL   Osteoarthritis Cartilage 13:697-708(2005).
//
RX   PubMed=19787792; DOI=10.1002/gcc.20717;
RA   Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S.E.,
RA   Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H.,
RA   Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W.,
RA   Buerger H., Aigner T., Gabbert H.E., Poremba C.;
RT   "Molecular characterization of commonly used cell lines for bone tumor
RT   research: a trans-European EuroBoNet effort.";
RL   Genes Chromosomes Cancer 49:40-51(2010).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=22057234; DOI=10.1038/ng.1004; PMCID=PMC3427908;
RA   Pansuriya T.C., van Eijk R., d'Adamo P., van Ruler M.A.J.H.,
RA   Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G.,
RA   Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L.,
RA   Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N.,
RA   Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M.,
RA   Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.;
RT   "Somatic mosaic IDH1 and IDH2 mutations are associated with
RT   enchondroma and spindle cell hemangioma in Ollier disease and Maffucci
RT   syndrome.";
RL   Nat. Genet. 43:1256-1261(2011).
//
RX   PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027;
RA   Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A.,
RA   Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A.,
RA   Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J.,
RA   Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E.,
RA   Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J.,
RA   Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C.,
RA   Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C.,
RA   Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P.,
RA   Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L.,
RA   Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R.,
RA   Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.;
RT   "The Cancer Cell Line Encyclopedia enables predictive modelling of
RT   anticancer drug sensitivity.";
RL   Nature 483:603-607(2012).
//
RX   PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476;
RA   Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E.,
RA   Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J.,
RA   Harris E., Monks A., Morris J.;
RT   "Sarcoma cell line screen of oncology drugs and investigational agents
RT   identifies patterns associated with gene and microRNA expression.";
RL   Mol. Cancer Ther. 14:2452-2462(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//
RX   PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737;
RA   Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C.,
RA   Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K.,
RA   Greninger P., McDermott U., Garnett M.J., Jenkins R.L.,
RA   Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y.,
RA   Goyal L., Ferrone C.R., Zhu A.X.-X., Joung J.K., Shokat K.M., Benes C.H.,
RA   El-Bardeesy N.;
RT   "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity
RT   and SRC dependence in intrahepatic cholangiocarcinoma.";
RL   Cancer Discov. 6:727-739(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=29853780; DOI=10.1155/2018/3082526; PMCID=PMC5964616;
RA   Salawu A., Wright K., Al-Kathiri A., Wyld L., Reed M.W.R., Sisley K.;
RT   "Sister chromatid exchange and genomic instability in soft tissue
RT   sarcomas: potential implications for response to DNA-damaging
RT   treatments.";
RL   Sarcoma 2018:3082526.1-3082526.8(2018).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. 3rd, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//