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Cellosaurus SH-SY5Y-SPA4CT (CVCL_0523)

[Text version]
Cell line name SH-SY5Y-SPA4CT
Accession CVCL_0523
Resource Identification Initiative To cite this cell line use: SH-SY5Y-SPA4CT (RRID:CVCL_0523)
Comments Population: Caucasian.
Transfected with: HGNC; 620; APP (1-19 in frame with 672-770).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line

PubMed=8243673; DOI=10.1016/0014-5793(93)80446-2
Dyrks T., Dyrks E., Monning U., Urmoneit B., Turner J., Beyreuther K.
Generation of beta A4 from the amyloid protein precursor and fragments thereof.
FEBS Lett. 335:89-93(1993)

Cell line databases/resources MCCL; MCC:0000422
cancercelllines; CVCL_0523
Encyclopedic resources Wikidata; Q54953228
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19