ID   SH-SY5Y-SPA4CT
AC   CVCL_0523
SY   SH-SY5Y SPA4CT; SHSY5Y-SPA4CT; SPA4CT
DR   MCCL; MCC:0000422
DR   cancercelllines; CVCL_0523
DR   Wikidata; Q54953228
RX   PubMed=8243673;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:620; APP (Note=With p.Val20_Met671del = SPA4CT).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0019 ! SH-SY5Y
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 21
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RX   PubMed=8243673; DOI=10.1016/0014-5793(93)80446-2;
RA   Dyrks T., Dyrks E., Monning U., Urmoneit B., Turner J., Beyreuther K.;
RT   "Generation of beta A4 from the amyloid protein precursor and
RT   fragments thereof.";
RL   FEBS Lett. 335:89-93(1993).
//