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Cellosaurus SG231 (CVCL_0519)

[Text version]
Cell line name SG231
Synonyms PCI:SG231; PCI-SG231; PCI:SG-231
Accession CVCL_0519
Resource Identification Initiative To cite this cell line use: SG231 (RRID:CVCL_0519)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Genomics; Whole exome sequencing.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr125Pro (c.373A>C); ClinVar=VCV000376666; Zygosity=Unspecified (DepMap=ACH-001857).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2126; DepMap=ACH-001857

Markers:
AmelogeninX
CSF1PO10 (ATCC=CRL-2126)
10,11 (DepMap=ACH-001857)
D3S135817
D5S81812
D7S82011
D8S117912,13
D13S3179,10
D16S5399,14 (DepMap=ACH-001857)
14 (ATCC=CRL-2126)
D18S5118
D21S1129
FGA21,21.2
Penta D12,15
Penta E10,13
TH018,9
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=2176543; DOI=10.1002/gcc.2870020408
Patrick Daniel Storto, Susan L. Saidman, Anthony Jacob Demetris, Eric Letessier, Theresa L. Whiteside, Susanne M. Gollin;
Chromosomal breakpoints in cholangiocarcinoma cell lines.
Genes Chromosomes Cancer 2:300-310(1990)

CLPUB00275
Sebastian Zach, Emrullah Birgin, Felix Ruckert;
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Supriya Kumar Saha, John D. Gordan, Benjamin P. Kleinstiver, Phuong Vu, Mortada S. Najem, Jia-Chi Yeo, Lei Shi, Yasutaka Kato, Rebecca S. Levin, James T. Webber, Leah J. Damon ...Show all 28 authors... , Regina K. Egan, Patricia Greninger, Ultan McDermott, Mathew J. Garnett, Roger L. Jenkins, Kimberly M. Rieger-Christ, Travis B. Sullivan, Aram Francis Hezel, Andrew S. Liss, Yusuke Mizukami, Lipika Goyal, Cristina Rosa Ferrone, Andrew Xiu-Xuan Zhu, Jae Keith Joung, Kevan Michael Shokat, Cyril Henri Benes, Nabeel M. Bardeesy; Show fewer authors
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line collections (Providers) ATCC; CRL-2126 - Discontinued
Cell line databases/resources MCCL; MCC:0000417
cancercelllines; CVCL_0519
Cell_Model_Passport; SIDM01852
DepMap; ACH-001857
Anatomy/cell type resources BTO; BTO_0002935
Biological sample resources BioSample; SAMN03472551
Encyclopedic resources Wikidata; Q54953156
Experimental variables resources EFO; EFO_0022554
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26