Cellosaurus SNU-475 (CVCL_0497)
Cell line name | SNU-475 | ||||||||||||||||||||||||||||||||||||
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Synonyms | SNU475; NCI-SNU-475 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0497 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: SNU-475 (RRID:CVCL_0497) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: Liver Cancer Model Repository (LIMORE). Part of: MD Anderson Cell Lines Project. Part of: Seoul National University (SNU) cell line collection. Population: Korean. Doubling time: 66 hours (PubMed=7543080); 35.6 hours (PubMed=31378681). Karyotypic information: Has lost chromosome Y. Microsatellite instability: Stable (MSS) (Sanger). Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV). Omics: Genomics; DNA methylation analysis. Omics: Genomics; Whole exome sequencing. Omics: Genomics; Whole genome sequencing. Omics: Phenotyping; Drug screening. Omics: Proteomics; Expression; Reverse-phase protein array. Omics: Proteomics; Quantitative. Omics: Transcriptomics; Microarray. Omics: Transcriptomics; miRNA profiling; Microarray. Omics: Transcriptomics; RNAseq. Omics: Variations; Array-based CGH. Omics: Variations; SNP array analysis. Derived from site: In situ; Liver; UBERON=UBERON_0002107. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 43Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=CRL-2236; Cosmic-CLP=909739; KCLB=00475; PubMed=25877200; PubMed=31378681 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | Info; LCCL; -; https://lccl.zucmanlab.com/hcc/cellLines/SNU475 Info; MCLP; -; https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=7543080; DOI=10.1002/ijc.2910620308 PubMed=8824565; DOI=10.1002/(SICI)1097-0215(19960917)67:6<898::AID-IJC22>3.0.CO;2-X PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416 PubMed=16616112; DOI=10.1016/j.cancergencyto.2005.08.022 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=23505090; DOI=10.1002/hep.26402 PubMed=23887712; DOI=10.1038/ncomms3218; PMCID=PMC3731665 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=25574106; DOI=10.3748/wjg.v21.i1.311; PMCID=PMC4284350 PubMed=25877200; DOI=10.1038/nature14397 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31063779; DOI=10.1053/j.gastro.2019.05.001 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-2236
KCLB; 00475 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009101
cancercelllines; CVCL_0497 Cell_Model_Passport; SIDM01196 Cosmic-CLP; 909739 DepMap; ACH-000422 IGRhCellID; SNU475 LIMORE; SNU475 LINCS_LDP; LCL-1937 Lonza; 452 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO_0003189 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471846
BioSample; SAMN03473134 BioSample; SAMN10987958 | ||||||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 811 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308787
ChEMBL-Targets; CHEMBL1075586 GDSC; 909739 PharmacoDB; SNU475_1465_2019 PubChem_Cell_line; CVCL_0497 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54955204 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002350 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM481449 GEO; GSM565920 GEO; GSM887630 GEO; GSM888715 GEO; GSM936783 GEO; GSM1670472 GEO; GSM2551590 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 684201
Cosmic; 871512 Cosmic; 873403 Cosmic; 909739 Cosmic; 928145 Cosmic; 2023871 Cosmic; 2162533 Cosmic; 2321038 IARC_TP53; 6310 IARC_TP53; 21143 LiGeA; CCLE_299 Progenetix; CVCL_0497 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610
EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 10-Apr-2025 | ||||||||||||||||||||||||||||||||||||
Version number | 44 |