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Cellosaurus L3.6pl (CVCL_0384)

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Cell line name L3.6pl
Synonyms L3.6PL; L3_6PL; L3.6 pancreas-liver; Colo357L3.6pl
Accession CVCL_0384
Resource Identification Initiative To cite this cell line use: L3.6pl (RRID:CVCL_0384)
Comments Population: African American.
Doubling time: 16 hours (PubMed=10935470).
Omics: Transcriptomics; miRNA profiling; Microarray.
Derived from site: Metastatic; Celiac axis lymph node; UBERON=UBERON_0002508.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
Disease Pancreatic adenosquamous carcinoma (NCIt: C5721)
Squamous cell carcinoma of pancreas (ORDO: Orphanet_424039)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8147 (L3.3)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

PubMed=10935470; DOI=10.1038/sj.neo.7900005; PMCID=PMC1764837
Christiane J. Bruns, Matthew T. Harbison, Hiroki Kuniyasu, Ines Eue, Isaiah Joshua Fidler;
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice.
Neoplasia 1:50-62(1999)

PubMed=20037478; DOI=10.4161/cbt.8.21.9685; PMCID=PMC2824894
Oliver A. Kent, Michael E. Mullendore, Eric A. Wentzel, Pedro Lopez-Romero, Aik-Choon Tan, Hector Alvarez, Kristen M. West, Michael F. Ochs, Manuel Hidalgo, Dan E. Arking, Anirban Maitra, Joshua T. Mendell;
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Cancer Biol. Ther. 8:2013-2024(2009)

Cross-references
Cell line databases/resources MCCL; MCC:0000279
cancercelllines; CVCL_0384
Anatomy/cell type resources BTO; BTO_0003441
Chemistry resources ChEMBL-Cells; CHEMBL4630602
ChEMBL-Targets; CHEMBL4630703
PubChem_Cell_line; CVCL_0384
Encyclopedic resources Wikidata; Q54901024
Polymorphism and mutation databases Cosmic; 1198211
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23