ID   L3.6pl
AC   CVCL_0384
SY   L3.6PL; L3_6PL; L3.6 pancreas-liver; Colo357L3.6pl
DR   BTO; BTO_0003441
DR   MCCL; MCC:0000279
DR   cancercelllines; CVCL_0384
DR   ChEMBL-Cells; CHEMBL4630602
DR   ChEMBL-Targets; CHEMBL4630703
DR   Cosmic; 1198211
DR   PubChem_Cell_line; CVCL_0384
DR   Wikidata; Q54901024
RX   PubMed=10935470;
RX   PubMed=20037478;
CC   Population: African American.
CC   Doubling time: 16 hours (PubMed=10935470).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Derived from site: Metastatic; Celiac axis lymph node; UBERON=UBERON_0002508.
DI   NCIt; C5721; Pancreatic adenosquamous carcinoma
DI   ORDO; Orphanet_424039; Squamous cell carcinoma of pancreas
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_8147 ! L3.3
SX   Female
AG   77Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   PubMed=10935470; DOI=10.1038/sj.neo.7900005; PMCID=PMC1764837;
RA   Bruns C.J., Harbison M.T., Kuniyasu H., Eue I., Fidler I.J.;
RT   "In vivo selection and characterization of metastatic variants from
RT   human pancreatic adenocarcinoma by using orthotopic implantation in
RT   nude mice.";
RL   Neoplasia 1:50-62(1999).
//
RX   PubMed=20037478; DOI=10.4161/cbt.8.21.9685; PMCID=PMC2824894;
RA   Kent O.A., Mullendore M.E., Wentzel E.A., Lopez-Romero P., Tan A.-C.,
RA   Alvarez H., West K.M., Ochs M.F., Hidalgo M., Arking D.E., Maitra A.,
RA   Mendell J.T.;
RT   "A resource for analysis of microRNA expression and function in
RT   pancreatic ductal adenocarcinoma cells.";
RL   Cancer Biol. Ther. 8:2013-2024(2009).
//