ID   L3.6pl
AC   CVCL_0384
SY   L3.6PL; L3_6PL; L3.6 pancreas-liver; Colo357L3.6pl
DR   BTO; BTO_0003441
DR   MCCL; MCC:0000279
DR   cancercelllines; CVCL_0384
DR   ChEMBL-Cells; CHEMBL4630602
DR   ChEMBL-Targets; CHEMBL4630703
DR   Cosmic; 1198211
DR   PubChem_Cell_line; CVCL_0384
DR   Wikidata; Q54901024
RX   PubMed=10935470;
RX   PubMed=20037478;
CC   Population: African American.
CC   Doubling time: 16 hours (PubMed=10935470).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Derived from site: Metastatic; Celiac axis lymph node; UBERON=UBERON_0002508.
DI   NCIt; C5721; Pancreatic adenosquamous carcinoma
DI   ORDO; Orphanet_424039; Squamous cell carcinoma of pancreas
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_8147 ! L3.3
SX   Female
AG   77Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   PubMed=10935470; DOI=10.1038/sj.neo.7900005; PMCID=PMC1764837;
RA   Bruns, Christiane J.
RA   Harbison, Matthew T.
RA   Kuniyasu, Hiroki
RA   Eue, Ines
RA   Fidler, Isaiah Joshua
RT   "In vivo selection and characterization of metastatic variants from
RT   human pancreatic adenocarcinoma by using orthotopic implantation in
RT   nude mice.";
RL   Neoplasia 1:50-62(1999).
//
RX   PubMed=20037478; DOI=10.4161/cbt.8.21.9685; PMCID=PMC2824894;
RA   Kent, Oliver A.
RA   Mullendore, Michael E.
RA   Wentzel, Eric A.
RA   Lopez-Romero, Pedro
RA   Tan, Aik-Choon
RA   Alvarez, Hector
RA   West, Kristen M.
RA   Ochs, Michael F.
RA   Hidalgo, Manuel
RA   Arking, Dan E.
RA   Maitra, Anirban
RA   Mendell, Joshua T.
RT   "A resource for analysis of microRNA expression and function in
RT   pancreatic ductal adenocarcinoma cells.";
RL   Cancer Biol. Ther. 8:2013-2024(2009).
//