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Cellosaurus JR-St (CVCL_0365)

[Text version]
Cell line name JR-St
Synonyms JRST; JR-1
Accession CVCL_0365
Secondary accession CVCL_W525
Resource Identification Initiative To cite this cell line use: JR-St (RRID:CVCL_0365)
Comments Population: Japanese.
Doubling time: 72 hours (Note=At 20th passage) (PubMed=2562403); 35 hours (Note=At 30th passage) (PubMed=1848829).
Derived from site: Metastatic; Cerebrospinal fluid; UBERON=UBERON_0001359.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Val173Met (c.517G>A); ClinVar=VCV000233951; Zygosity=Unspecified (PubMed=1370612).
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=2562403
Terano A., Nakada R., Mutoh H., Hiraishi H., Ota S., Kimura K., Aoyama H., Sugimoto T., Shiga J., Itoh Y.
Establishment and characterization of a tumor marker producing cell line (JR-1) derived from a gastric scirrhous cancer.
Hum. Cell 2:307-309(1989)

PubMed=1848829; DOI=10.1007/BF02779502
Terano A., Nakada R., Mutoh H., Hiraishi H., Ota S., Shiina S., Shimada T., Itoh Y., Kimura K., Shiga J., Sugimoto T.
Characterization of a newly established cell line (JR-St) derived from human gastric signet ring cell cancer, producing tumor markers.
Gastroenterol. Jpn. 26:7-13(1991)

PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0
Matozaki T., Sakamoto C., Matsuda K., Suzuki T., Konda Y., Nakano O., Wada K., Uchida T., Nishisaki H., Nagao M., Kasuga M.
Missense mutations and a deletion of the p53 gene in human gastric cancer.
Biochem. Biophys. Res. Commun. 182:215-223(1992)

DOI=10.1016/B978-0-12-333530-2.50014-9
Sekiguchi M., Suzuki T.
Gastric tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York (1994)

Cross-references
Cell line databases/resources MCCL; MCC:0000259
cancercelllines; CVCL_0365
Encyclopedic resources Wikidata; Q54899058
Polymorphism and mutation databases Cosmic; 877045
Cosmic; 918494
IARC_TP53; 970
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number15