ID   JR-St
AC   CVCL_0365
AS   CVCL_W525
SY   JRST; JR-1
DR   MCCL; MCC:0000259
DR   cancercelllines; CVCL_0365
DR   Cosmic; 877045
DR   Cosmic; 918494
DR   IARC_TP53; 970
DR   Wikidata; Q54899058
RX   DOI=10.1016/B978-0-12-333530-2.50014-9;
RX   PubMed=1370612;
RX   PubMed=1848829;
RX   PubMed=2562403;
CC   Population: Japanese.
CC   Doubling time: 72 hours (Note=At 20th passage) (PubMed=2562403); 35 hours (Note=At 30th passage) (PubMed=1848829).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val173Met (c.517G>A); ClinVar=VCV000233951; Zygosity=Unspecified (PubMed=1370612).
CC   Derived from site: Metastatic; Cerebrospinal fluid; UBERON=UBERON_0001359.
DI   NCIt; C5250; Gastric signet ring cell adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   37Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 16
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RX   DOI=10.1016/B978-0-12-333530-2.50014-9;
RA   Sekiguchi M., Suzuki T.;
RT   "Gastric tumor cell lines.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York; USA (1994).
//
RX   PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0;
RA   Matozaki T., Sakamoto C., Matsuda K., Suzuki T., Konda Y., Nakano O.,
RA   Wada K., Uchida T., Nishisaki H., Nagao M., Kasuga M.;
RT   "Missense mutations and a deletion of the p53 gene in human gastric
RT   cancer.";
RL   Biochem. Biophys. Res. Commun. 182:215-223(1992).
//
RX   PubMed=1848829; DOI=10.1007/BF02779502;
RA   Terano A., Nakada R., Mutoh H., Hiraishi H., Ota S., Shiina S.,
RA   Shimada T., Itoh Y., Kimura K., Shiga J., Sugimoto T.;
RT   "Characterization of a newly established cell line (JR-St) derived
RT   from human gastric signet ring cell cancer, producing tumor markers.";
RL   Gastroenterol. Jpn. 26:7-13(1991).
//
RX   PubMed=2562403;
RA   Terano A., Nakada R., Mutoh H., Hiraishi H., Ota S., Kimura K.,
RA   Aoyama H., Sugimoto T., Shiga J., Itoh Y.;
RT   "Establishment and characterization of a tumor marker producing cell
RT   line (JR-1) derived from a gastric scirrhous cancer.";
RL   Hum. Cell 2:307-309(1989).
//