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Cellosaurus IN157 (CVCL_0350)

[Text version]
Cell line name IN157
Synonyms IN-157; IN/157; IN 157
Accession CVCL_0350
Resource Identification Initiative To cite this cell line use: IN157 (RRID:CVCL_0350)
Comments Problematic cell line: Contaminated. Shown to be a RD derivative (PubMed=1620276). Originally thought to originate from an oligodendroglioma.
Population: Caucasian.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (PubMed=1620276).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line

PubMed=2437255; DOI=10.1007/BF00195610
Kennedy P.G.E., Watkins B.A., LaThangue N.B., Clements G.B., Thomas D.G.T.
A cultured human oligodendroglioma cell line and herpes simplex virus-infected cells share antigenic determinants.
J. Neurooncol. 4:389-396(1987)

PubMed=1620276; DOI=10.1111/j.1365-2990.1992.tb00777.x
Venter D.J., Stratton M.R., Noble M.D.
Molecular genetic study showing that the IN/157 'oligodendroglioma' cell line has been contaminated by rhabdomyosarcoma (RD) cells.
Neuropathol. Appl. Neurobiol. 18:159-169(1992)

Cell line databases/resources MCCL; MCC:0000244
cancercelllines; CVCL_0350
Encyclopedic resources Wikidata; Q54897693
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20