ID   IN157
AC   CVCL_0350
SY   IN-157; IN/157; IN 157
DR   MCCL; MCC:0000244
DR   cancercelllines; CVCL_0350
DR   Wikidata; Q54897693
RX   PubMed=1620276;
RX   PubMed=2437255;
CC   Problematic cell line: Contaminated. Shown to be a RD derivative (PubMed=1620276). Originally thought to originate from an oligodendroglioma.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (PubMed=1620276).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1649 ! RD
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
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RX   PubMed=1620276; DOI=10.1111/j.1365-2990.1992.tb00777.x;
RA   Venter D.J., Stratton M.R., Noble M.D.;
RT   "Molecular genetic study showing that the IN/157 'oligodendroglioma'
RT   cell line has been contaminated by rhabdomyosarcoma (RD) cells.";
RL   Neuropathol. Appl. Neurobiol. 18:159-169(1992).
//
RX   PubMed=2437255; DOI=10.1007/BF00195610;
RA   Kennedy P.G.E., Watkins B.A., LaThangue N.B., Clements G.B.,
RA   Thomas D.G.T.;
RT   "A cultured human oligodendroglioma cell line and herpes simplex
RT   virus-infected cells share antigenic determinants.";
RL   J. Neurooncol. 4:389-396(1987).
//